Registration Dossier

Ecotoxicological information

Toxicity to aquatic algae and cyanobacteria

Administrative data

Endpoint:
toxicity to aquatic algae and cyanobacteria
Type of information:
calculation (if not (Q)SAR)
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
results derived from a valid (Q)SAR model and falling into its applicability domain, with adequate and reliable documentation / justification
Remarks:
Guidance on information requirements and chemical safety assessment Chapter R.6: QSARs and grouping of chemicals

Data source

Reference
Reference Type:
other: The Estimation Programs Interface (EPI) Suite TM
Title:
Unnamed
Year:
2017

Materials and methods

Principles of method if other than guideline:
Estimation of the toxicity to aquatic algae by the use of ECOSAR.
GLP compliance:
no

Test material

Reference
Name:
Unnamed
Type:
Constituent

Test organisms

Test organisms (species):
other: Green Algae

Results and discussion

Effect concentrations
Key result
Duration:
96 h
Dose descriptor:
EC50
Effect conc.:
80.84 mg/L
Nominal / measured:
estimated
Conc. based on:
test mat.

Applicant's summary and conclusion

Conclusions:
For the toxicity to aquatic algae, an EC50 value of 80.84 mg/L could be calculated by ECOSAR. This value is in line with the information in the Annex III Inventory (ECHA list). Here it is mentioned, that the Danish QSAR database contains information indicating that the substance has a 96h EC50 to green algae of 80.72 mg/L.