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EC number: 201-063-9 | CAS number: 77-85-0
Toxicity to aquatic algae and cyanobacteria
Administrative data
Link to relevant study record(s)
- Endpoint:
- toxicity to aquatic algae and cyanobacteria
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 1994 or before
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: Data peer-reviewed by OECD and cited in OECD SIDS Dossier to be performed according to an OECD guideline, short abstract available.
- Reason / purpose for cross-reference:
- reference to same study
- Reason / purpose for cross-reference:
- reference to other study
- Qualifier:
- according to guideline
- Guideline:
- other: OECD Guideline, not further specified
- Principles of method if other than guideline:
- The toxicity of trimethylopropane was determined on the green algae Pseudokirchneriella subcapitata (reported as Selenastrum carpicornutum) within 72h, based on biomass.
- GLP compliance:
- no
- Specific details on test material used for the study:
- Details on properties of test surrogate or analogue material (migrated information):
Not applicable - Analytical monitoring:
- not specified
- Details on sampling:
- Details not provided
- Vehicle:
- not specified
- Details on test solutions:
- Details not provided
- Test organisms (species):
- Raphidocelis subcapitata (previous names: Pseudokirchneriella subcapitata, Selenastrum capricornutum)
- Details on test organisms:
- Details not provided
- Test type:
- not specified
- Water media type:
- freshwater
- Total exposure duration:
- 72 h
- Post exposure observation period:
- Not provided
- Hardness:
- Not provided
- Test temperature:
- Not provided
- pH:
- Not provided
- Dissolved oxygen:
- Not provided
- Salinity:
- Not applicable
- Nominal and measured concentrations:
- Nominal concentrations are not provided
- Details on test conditions:
- Not provided
- Reference substance (positive control):
- not specified
- Duration:
- 72 h
- Dose descriptor:
- EC50
- Effect conc.:
- > 1 000 mg/L
- Basis for effect:
- biomass
- Details on results:
- Details are not provided
- Results with reference substance (positive control):
- Not provided / not applicable
- Reported statistics and error estimates:
- Not provided
- Validity criteria fulfilled:
- not specified
- Conclusions:
- The 72-h EbC50 was determined to be greater than 1000 mg/L.
- Executive summary:
The toxicity of trimethylopropane on the green algae Pseudokirchneriella subcapitata (reported as Selenastrum carpicornutum) was tested according to an OECD guideline. The 72-h EbC50 was determined to be greater than 1000 mg/L (based on nominal concentrations).
Being performed by EA Japan according to a OECD-Guideline, the study is considered to be acceptable.
Reference: EA Japan/SIDS, <= 1994
Reference
No remarks
Description of key information
Key value for chemical safety assessment
- EC50 for freshwater algae:
- 1 000 mg/L
Additional information
Assessment is by read-across to the source substance trimethylolpropane (CAS No: 77-99-6).
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