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Partition coefficient

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Reference
Endpoint:
partition coefficient
Type of information:
experimental study
Adequacy of study:
key study
Study period:
From 14 July 2017 to 31 August 2017
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Remarks:
GLP compliant
Qualifier:
according to
Guideline:
OECD Guideline 117 (Partition Coefficient (n-octanol / water), HPLC Method)
Deviations:
no
GLP compliance:
yes (incl. certificate)
Remarks:
Date of the certificate: 30 June 2017
Type of method:
HPLC method
Partition coefficient type:
octanol-water
Analytical method:
high-performance liquid chromatography
Key result
Type:
log Pow
Partition coefficient:
1.8
Remarks on result:
other: pH not applicable

There was no UV traces observed from the test item therefore the MS Chromatogram were evaluated. The retention time difference between the UV and MS detector was 0.141 min (Attachment No.8)

The chromatogram of the test item are shown in Attachment 1. The chromatogram of reference compounds are shown in Attachments 2, 3, 4, 5, 6 and 7.

Conclusions:
The partition coefficient of Fluorosulfonic Adduct was determined to be 1.8.
Executive summary:

The determination of the partition coefficient of the test item, Fluorosulfonic Adduct, was carried out under GLP compliance, using a HPLC method according to OECD Guideline No. 117.

The determination is based on the measurement of the retention time of FLUOROSULFONIC ADDUCT on C8 stationary phase with methanol:water eluent (according to OECD 117 guideline).

The log POW of the test item is 1.8.

Description of key information

The log Kow of Fluorosulfonic Adduct was determined to be 1.8.

Key value for chemical safety assessment

Log Kow (Log Pow):
1.8
at the temperature of:
20 °C

Additional information

The determination of the partition coefficient of the test item, Fluorosulfonic Adduct, was carried out under GLP compliance, using a HPLC method according to OECD Guideline No. 117.

The determination was based on the measurement of the retention time of FLUOROSULFONIC ADDUCT on C8 stationary phase with methanol:water eluent (according to OECD 117 guideline).