Registration Dossier
Registration Dossier
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The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
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EC number: 906-936-4 | CAS number: -
Repeated dose toxicity: other routes
Administrative data
- Endpoint:
- sub-chronic toxicity: other route
- Type of information:
- read-across based on grouping of substances (category approach)
- Adequacy of study:
- supporting study
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- other: secondary literature / original data/study not available / peer-reviewed
- Justification for type of information:
- Read across is based on the category approach. Please refer to attached category document.
Data source
Reference
- Reference Type:
- secondary source
- Title:
- Triethylene Glycol. Review of Phase IV response submissions in support of FIFRA 88.
- Author:
- EPA
- Year:
- 1 993
Materials and methods
- GLP compliance:
- not specified
Test material
- Reference substance name:
- 2,2'-(ethylenedioxy)diethanol
- EC Number:
- 203-953-2
- EC Name:
- 2,2'-(ethylenedioxy)diethanol
- Cas Number:
- 112-27-6
- Molecular formula:
- C6H14O4
- IUPAC Name:
- 2,2'-[ethane-1,2-diylbis(oxy)]diethanol
Constituent 1
Test animals
- Species:
- monkey
- Strain:
- not specified
- Sex:
- not specified
Administration / exposure
- Route of administration:
- other: inhalative and orally
- Duration of treatment / exposure:
- 24 months
Results and discussion
Results of examinations
- Details on results:
- Monkeys were exposed continuously to saturated/near saturated concentrations of TEG vapors or orally in egg nog of 50 (0.25 cc) - 100 (0.5 cc) times the glycol the animals could absorb by breathing air saturated with glycol, did not adversely effect either the body physiological functions or the organ histpathology.
Effect levels
- Basis for effect level:
- other: see 'Remark'
- Remarks on result:
- not measured/tested
- Remarks:
- Effect level not specified
Target system / organ toxicity
- Critical effects observed:
- not specified
Applicant's summary and conclusion
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
