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EC number: 284-395-7 | CAS number: 84870-65-5
INDIVIDUAL DAILY AND INDIVIDUAL MEAN SCORES FOR DERMAL IRRITATION/CORROSION
TEST MATERIAL: DISPERSIONSBLAU F-60 768
INDIVIDUAL SCORES – RABBIT NUMBER:
24, 48 & 72 HOURS
*MEAN VALUES = means of the 24, 48 and 72-hour readings.
R = reaction extending 3 – 4 cm beyond treatment site
Oe = oedema extending ventrally below treatment site
D = desquamation
A study was performed to assess the irritancy potential of the test material to the skin of the New Zealand White rabbit. The method used followed that described in the OECD Guidelines for Testing of Chemicals (1981) No. 404 "Acute Dermal Irritation/Corrosion''. The results of the study will be used to classify the test material according to the E.E.C. Directive of 29 July 1983 83/467/EEC adapting Council Directive 67/548/EEC on the regulations relating to classification, packaging and labelling of dangerous substances.
A single, 4-hour, semi-occluded dermal application of the test material to the intact skin of three rabbits produced very slight or well-defined erythema and slight to severe oedema. Very slight erythema was confined to one treatment site on day seven. Other adverse dermal reactions were confined to desquamation at two treatment sites at this time. All treatment sites appeared normal on day fourteen.
Based on the results of this study, the substance is not classified as skin irritant according to CLP criteria.
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