Registration Dossier

Diss Factsheets

Administrative data

Endpoint:
partition coefficient
Type of information:
experimental study
Adequacy of study:
key study
Study period:
05.02.2016
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2016
Report date:
2016

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
EU Method A.8 (Partition Coefficient - HPLC Method)
GLP compliance:
no
Type of method:
HPLC method

Test material

Constituent 1
Chemical structure
Reference substance name:
(1'r,4'r)-4-butyl-4'-(4-ethoxy-2,3-difluorophenyl)-1,1'-bi(cyclohexane)
EC Number:
610-337-0
Cas Number:
473257-15-7
Molecular formula:
C24H36F2O
IUPAC Name:
(1'r,4'r)-4-butyl-4'-(4-ethoxy-2,3-difluorophenyl)-1,1'-bi(cyclohexane)

Results and discussion

Partition coefficient
Type:
log Pow
Partition coefficient:
> 6.5
Temp.:
25 °C
pH:
6.1

Applicant's summary and conclusion

Executive summary:

The logPOW of the test substance was > 6.5.