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EC number: 946-382-0 | CAS number: -
A skin irritation test was performed with PEMP according to OECD/ EC guidelines and GLP principles. One rabbit was exposed semi-occlusively for 3 minutes, 1hour and 4 hours. Subsequently two additional rabbits were exposed semi-occlusively for 4 hours.
Exposure for 3 minutes did not induce adverse skin effects. Exposure for 1 hour gave an erythema score of 1 one hour after removal of the test substance and at the 24- and 48-hour observations. The erythema had fully resolved after 72 hours. Exposure for 4 hours resulted in very slight erythema at one of the treated skin site one hour after patch removal, at all treated skin sites at the 24- and 48-hour observations and at two treated skins at the 72-hour observation. One treated skin appeared normal at the 72-hour observation and two treated skin sites appeared normal after 7 days.
Based on these data, PEMP was found to be not corrosive and not irritating to the skin, therefore the substance is not classified according to Regulation (EC) 1272/2008.
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