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Physical & Chemical properties

Vapour pressure

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Reference
Endpoint:
vapour pressure
Type of information:
experimental study
Adequacy of study:
key study
Study period:
04 February 2016 - 05 February 2016
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
according to guideline
Guideline:
EU Method A.4 (Vapour Pressure)
Deviations:
no
Qualifier:
according to guideline
Guideline:
OECD Guideline 104 (Vapour Pressure Curve)
Version / remarks:
2006
Deviations:
no
Qualifier:
according to guideline
Guideline:
other: OECD Guideline 113 (Screening Test for Thermal Stability and Stability in Air)
Version / remarks:
1981
Deviations:
no
GLP compliance:
no
Remarks:
Study was not performed under GLP, however the test facility was GLP-compliant.
Type of method:
dynamic method
Remarks:
Vapour-liquid equilibrium (VLE)
Key result
Temp.:
20 °C
Vapour pressure:
0.24 hPa
Remarks on result:
other: Calculated by extrapolation of the measured vapour pressure curve
Temp.:
25 °C
Vapour pressure:
0.32 hPa
Remarks on result:
other: Calculated by extrapolation of the measured vapour pressure curve
Temp.:
50 °C
Vapour pressure:
1.22 hPa
Remarks on result:
other: Calculated by extrapolation of the measured vapour pressure curve

Reaction and/or decomposition of the test material was not observed during the test.

Table 1 Vapour pressure results at various temperatures

Temperature (°C)

Vapour pressure (hPa)

Condition

106.1

13.5

measured up

131.0

28.2

measured up

146.2

45.6

measured up

154.0

59.6

measured up

161.8

74.8

measured up

166.1

84.9

measured up

164.0

79.8

measured down

159.8

69.3

measured down

148.6

50.2

measured down

Table 2 Estimated vapour pressures

Temperature (°C)

Vapour pressure (hPa)

20

0.24

25

0.32

50

1.22

Conclusions:
The vapour pressure of the test item was determined to be 0.24, 0.32 and 1.22 hPa at 20, 25 and 50 °C, respectively.
Executive summary:

Vapour pressure was determined by vapour-liquid equilibrium (dynamic method) according to OECD Guideline 104 and EU Method A.4. The vapour pressure of the test item was determined to be 0.24, 0.32 and 1.22 hPa at 20, 25 and 50 °C, respectively, calculated by extrapolation of the measured vapour pressure curve. The study was not performed under GLP, however the test facility was GLP-compliant. The study is considered to be reliable without restrictions (Klimisch 1).

Description of key information

The vapour pressure of the test item was determined to be 0.24, 0.32 and 1.22 hPa at 20, 25 and 50°C, respectively.

Key value for chemical safety assessment

Vapour pressure:
0.24 hPa
at the temperature of:
20 °C

Additional information

Vapour pressure was determined by vapour-liquid equilibrium (dynamic method) according to OECD Guideline 104 and EU Method A.4. The vapour pressure of the test item was calculated by extrapolation of the measured vapour pressure curve (2016). The study was not performed under GLP, however the test facility was GLP-compliant. The study is considered to be reliable without restrictions (Klimisch 1).