Registration Dossier
Registration Dossier
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EC number: 675-664-3 | CAS number: 39149-80-9
Endpoint summary
Administrative data
Description of key information
Experimental data on the potential of skin sensitisation of TBBP are not available.
QSAR Toolbox has identified one "Mechanistic Alert: Nucleophilic substitution at sp3 Carbon atom". Halogens act as a good leaving group when bonded to a sufficiently electrophilic centre where C-Hal bond is activated by the electron-withdrawing groups (R) and SN2 reaction is possible. Skin sensitizing potential increases in order Cl< Br< I.
Key value for chemical safety assessment
Skin sensitisation
Endpoint conclusion
- Endpoint conclusion:
- no study available
Respiratory sensitisation
Endpoint conclusion
- Endpoint conclusion:
- no study available
Justification for classification or non-classification
Considering the only mechanistic profile of the substance, data are judged as inconclusive for the classification.
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