Registration Dossier
Registration Dossier
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EC number: 675-664-3 | CAS number: 39149-80-9
Endpoint summary
Administrative data
Key value for chemical safety assessment
Genetic toxicity in vitro
Description of key information
The potential of bacterial reverse mutation ability was assessed with Ames test.
Tert-Butyl 2-bromopropionate does not induce the increase of number of revertant more than 2 and increase related to dose compare to negative control for any bacterial strain with or without metabolic activator. Accordingly this substance was considered to be non-mutagenic under this test conditions.
Nevertheless, QSAR Toolbox has identified one structural alert for the in vivo and in vitro mutagenicity; structural alert is "Aliphatic alogens".
Endpoint conclusion
- Endpoint conclusion:
- no adverse effect observed (negative)
Genetic toxicity in vivo
Endpoint conclusion
- Endpoint conclusion:
- no study available
Additional information
Justification for classification or non-classification
Available data (i) mechanistic profile (QSAR Toolbox) and (ii) negative results in the Ames test are judged as inconclusive for the classification.
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