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Environmental fate & pathways

Bioaccumulation: aquatic / sediment

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Link to relevant study record(s)

Reference
Endpoint:
bioaccumulation in aquatic species: fish
Type of information:
(Q)SAR
Adequacy of study:
weight of evidence
Study period:
2010
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: The procedures applied are according to the REACH guidance the most appropriate way of assessing the bioaccumulation potential of the specific substances under consideration.
Justification for type of information:
QSAR prediction: migrated from IUCLID 5.6
Principles of method if other than guideline:
EPIweb QSAR based on a measured Log Kow which is based on the ratio between the octanol solubililty and CMC.
GLP compliance:
no
Test organisms (species):
other: QSAR
Type:
BCF
Value:
3.16 dimensionless
Basis:
other: QSAR calculation
Conclusions:
The procedures applied are according to the REACH guidance the most appropriate way of assessing the bioaccumulation potential of the specific substances under consideration.
Executive summary:

Based on a measured log Kow of 3.4 a log BCF is calculated of 2.4 assuming no metabolism as a worst-case.

Description of key information

Based on a measured log Kow  of -0.3 a BCF is calculated of 3.162 L/kg ww

Key value for chemical safety assessment

BCF (aquatic species):
3.162 L/kg ww

Additional information

Based on a measured log Kow of -0.3 for both the Oleyltetramine and cocotriamine using the slow-stirring method (OECD 123) a BCF is calculated of 3.162 L/kg ww for polyamines.

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