Registration Dossier

Administrative data

Endpoint:
partition coefficient
Type of information:
experimental study
Adequacy of study:
key study
Study period:
2009
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: Valid method

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2009
Report Date:
2009

Materials and methods

Principles of method if other than guideline:
Determination of solubility in octanol and in water and calculation of log Pow
Type of method:
other: Calculation from solubilities
Partition coefficient type:
octanol-water

Test material

Reference
Name:
Unnamed
Type:
Constituent
Details on test material:
- Name of test material: Licowax OP Flakes
- Appearance: Yellow-beige flakes

Results and discussion

Partition coefficientopen allclose all
Type:
Pow
Partition coefficient:
ca. 100
Temp.:
20 °C
pH:
ca. 7
Type:
log Pow
Partition coefficient:
ca. 2
Temp.:
20 °C
pH:
ca. 7
Details on results:
Pow and log Pow were calculated from equilibrium concentrations in octanol and in water (see below)

Any other information on results incl. tables

n-Octanol solubility:

Flask No.

Equilibration time at 20 °C [h]

Content of test substance [mg/L]

1

72

96

2

72

154

mean

---

125

Water solubility:

Flask No.

Equilibration time at
20 °C [h]

Content of test
substance [mg/L]

1

2

72
72

1

2

mean

---

2

 

Log Pow range:

Log (96/2)

=

1.7

Log (154/2)

=

1.9

Log (96/1)

=

2.0

Log (154/1)

=

2.2

Mean Log Pow= 2.0

Applicant's summary and conclusion

Conclusions:
The test substance has a log Pow of 2.0
Executive summary:

The log Pow of the test substance was calculated from the equilibrium concentrations in octanol and in water. The log Pow is 2.0