Registration Dossier

Administrative data

First-aid measures

General advice: Soiled, soaked clothing and shoes must be immediately removed, decontaminated and disposed of.

If inhaled:Get medical attention immediately. Move exposed person to fresh air. If it is suspected that fumes are still present, the rescuer should wear an appropriate mask or self-contained breathing apparatus. Keep person warm and at rest. If not breathing, if breathing is irregular or if respiratory arrest occurs, provide artificial respiration or oxygen by trained personnel. It may be dangerous to the person providing aid to give mouth-to-mouth resuscitation. If unconscious, place in recovery position and get medical attention immediately. Maintain an open airway. Loosen
tight clothing such as a collar, tie, belt or waistband. In case of inhalation of decomposition products in a fire, symptoms may be delayed. The exposed person may need to be kept under medical surveillance for 48 hours.

In case of skin contact: Get medical attention immediately. Flush contaminated skin with plenty of water.
Remove contaminated clothing and shoes. Wash contaminated clothing thoroughly with water before removing it, or wear gloves. Continue to rinse for at least 10 minutes. Chemical burns must be treated promptly by a physician.
Wash clothing before reuse. Clean shoes thoroughly before reuse.

In case of eye contact: Get medical attention immediately. Immediately flush eyes with plenty of water, occasionally lifting the upper and lower eyelids. Check for and remove any contact lenses. Continue to rinse for at least 10 minutes. Chemical burns must be treated promptly by a physician.

If swallowed: Get medical attention immediately. Wash out mouth with water. Remove dentures if any. Move exposed person to fresh air. Keep person warm and at rest. If material has been swallowed and the exposed person is conscious, give small quantities of water to drink. Stop if the exposed person feels sick as vomiting may be dangerous.
Do not induce vomiting unless directed to do so by medical personnel. If vomiting occurs, the head should be kept low so that vomit does not enter the lungs. Chemical burns must be treated promptly by a physician. Never give anything by mouth to an unconscious person. If unconscious, place in recovery position and get medical attention immediately. Maintain an open airway. Loosen tight clothing such as a collar, tie, belt or waistband.

Notes to physician: The product irritates the respiratory tract and may trigger sensitisation of the skin and respiratory tract. Treatment of acute irritation or bronchial constriction is primarily symptomatic. Following severe exposure the patient should be kept under medical review for at least 48 hours.

Fire-fighting measures

Suitable extinguishing media: Foam, CO2 or dry powder. Water spray may be used if no other available and then in copious quantities. Reaction between water and hot isocyanate may be vigorous. Prevent washings from entering water courses, keep fire exposed containers cool by spraying with water.

Unsuitable extinguishing media: High volume water jet.

Combustion products may include: carbon oxides (CO, CO2) nitrogen oxides (NO, NO2 etc.) hydrocarbons, isocyanate vapors and hydrogen cyanide.

In the event of fire and/or explosion do not breathe fumes.
Fire in vicinity poses risk of pressure build-up and rupture. Containers at risk from fire should be cooled with water and, if possible, removed from the danger area. Due to reaction with water producing CO2-gas, a hazardous build-up of pressure could result if contaminated containers are re-sealed. Containers may burst if overheated.
Fire-fighters should wear appropriate protective equipment and self-contained breathing apparatus (SCBA) with a full face-piece operated in positive pressure mode. PVC boots, gloves, safety helmet and protective clothing should be worn.
Do not allow contaminated extinguishing water to enter the soil, ground-water or surface waters.

Accidental release measures

Personal precautions: Immediately contact emergency personnel. Evacuate the area. Keep upwind to avoid inhalation of vapours. Clean-up should only be performed by trained personnel. People dealing with major spillages should wear full protective clothing including respiratory protection. Use suitable protective equipment. Keep unauthorized persons away.

Environmental precautions: Avoid dispersal of spilt material and runoff and contact with soil, waterways, drains and sewers.

Methods for cleaning up: If the product is in its solid form: Spilled MDI flakes should be picked up carefully. The area should be vacuum cleaned to remove remaining dust particles completely.
If the product is in its liquid form: Absorb spillages onto sand, earth or any suitable adsorbent material. Leave to react for at least 30 minutes. Do not absorb onto sawdust or other combustible materials. Shovel into open-top drums for further decontamination. Wash the spillage area with water. Test atmosphere for MDI vapour. Neutralise small spillages with decontaminant. Remove and dispose of residues. The compositions of liquid decontaminants are : (percentages by weight or volume) :
Decontaminant 1 : *- sodium carbonate : 5 - 10 % *- liquid detergent : 0.2 - 2 % *- water : to make up to 100 %
Decontaminant 2 : *- concentrated ammonia solution : 3 - 8 % *- liquid detergent : 0.2 - 2 % *- water : to make up to 100 %
Decontaminant 1 reacts slower with diisocyanates but is more environmentally friendly than decontaminant 2.
Decontaminant 2 contains ammonia. Ammonia presents health hazards. (See supplier safety information.)

Additional advice: -

Handling and storage

Handling: Provide sufficient air exchange and/or exhaust in work rooms. In all workplaces or parts of the plant where high concentrations of isocyanate aerosols and/or vapors may be generated (e.g. during pressure release, mold venting or when cleaning mixing heads with an air blast), appropriately located exhaust ventilation must be provided in order to prevent occupational exposure limits from being exceeded. The air should be drawn away from the personnel handling the product.
The efficiency of the ventilation system must be monitored regularly because of the possibility of blockage.
Atmospheric concentrations should be minimised and kept as low as reasonably practicable below the occupational exposure limit.

Contact with skin and eyes and inhalation of vapors must be avoided under all circumstances.
Keep equipment clean.
A basic essential in sampling, handling and storage is the prevention of contact with water. Keep stocks of decontaminant readily available. The compositions of liquid decontaminants are described under "Accidental release measures".

Storage : Store in accordance with local regulations. Store in original container protected from direct sunlight in a dry, cool and well-ventilated area, away from incompatible materials and food and drink. Keep container tightly closed and sealed until ready for use. Containers that have been opened must be carefully resealed and kept upright to prevent leakage. Do not store in unlabelled containers.
Use appropriate containment to avoid environmental contamination.
Suitable containers: Steel. Stainless steel.
Unsuitable containers: Copper., copper alloy and galvanised surfaces

Transport information

Land transport (ADR/RID)

UN number:
Not regulated
Shippingopen allclose all
Class:
Not regulated
Classification code:
Not regulated
Packaging group:
Not regulated
Labels:
Not regulated
SpecialProvisionsopen allclose all

Inland waterway transport (ADN(R))

UN number:
ID 9004
Shippingopen allclose all
Class:
9
Classification code:
--
Packaging group:
--
Labels:
--
Remarks
(PSN): DIPHENYLMETHAN-4,4'-DIISOCYANAT, Mixture



Marine transport (IMDG)

UN number:
Not regulated
Proper shipping name and description:
Not regulated
Chemical name:
Not regulated
Class:
Not regulated
Packaging group:
Not regulated
EmS code:
Not regulated
Labels:
Not regulated
Remarksopen allclose all

Air transport ICAO/IATA

UN number:
Not regulated
Proper shipping name and description:
Not regulated
Chemical name:
Not regulated
Class:
Not regulated
Packaging group:
Not regulated
Labels:
Not regulated
Remarksopen allclose all
SpecialProvisionsopen allclose all

Exposure controls / personal protection

Stability and reactivity

Disposal considerations