Registration Dossier
Registration Dossier
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EC number: 203-623-8 | CAS number: 108-86-1
Biodegradation in water: screening tests
Administrative data
Link to relevant study record(s)
- Endpoint:
- biodegradation in water: ready biodegradability
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 20 June - 12 Sep 1980
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- test procedure in accordance with national standard methods with acceptable restrictions
- Qualifier:
- according to guideline
- Guideline:
- other: Circular on Test Methods of New Chemical Substances (Japan), Biodegradation test
- GLP compliance:
- not specified
- Specific details on test material used for the study:
- STABILITY AND STORAGE CONDITIONS OF TEST MATERIAL
- Solubility and stability of the test substance in the solvent/vehicle: Not soluble in water, soluble in chloroform, benzene, alcohol and ether - Oxygen conditions:
- aerobic
- Inoculum or test system:
- activated sludge (adaptation not specified)
- Duration of test (contact time):
- 28 d
- Initial conc.:
- 30 other: ppm
- Based on:
- test mat.
- Parameter followed for biodegradation estimation:
- O2 consumption
- Parameter followed for biodegradation estimation:
- test mat. analysis
- Details on study design:
- TEST CONDITIONS
- Suspended solids concentration: 100 ppm
TEST SYSTEM
- Culturing apparatus: closed oxgen consumption measuring machine with 300 mL culture bottle
- Number of culture flasks/concentration: 1 (water + test substance), 3 (sludge + test sub.), 1 (sludge + reference sub.), 1 (sludge)
- Measuring equipment: Coulometer
- Test performed in closed vessels due to significant volatility of test substance: yes
CONTROL AND BLANK SYSTEM
- Inoculum blank: yes, 1 bottle - Reference substance:
- aniline
- Parameter:
- % degradation (O2 consumption)
- Value:
- 0
- Sampling time:
- 28 d
- Parameter:
- % degradation (test mat. analysis)
- Value:
- 0
- Sampling time:
- 28 d
- Results with reference substance:
- The oxygen consumption for aniline in the above used test system reached 61% after 7 days.
- Interpretation of results:
- not readily biodegradable
Reference
Description of key information
Not readily biodegradable: 0% after 28 d
Key value for chemical safety assessment
- Biodegradation in water:
- under test conditions no biodegradation observed
Additional information
There is one study available, which investigated the biodegradation of the test substance in water according to Circular on Test Methods of New Chemical Substances (Japan), Biodegradation test. Microorganisms were inoculated with 30 ppm test substance in closed bottles for two weeks and oxygen consumption as well as GC/FID was followed to estimate biodegradation.
After two weeks the test substance was degraded by 0% based on analysis of the test substance and 0% based on O2 consumption. Therefore, it was concluded that the test substance is not readily biodegradable according to the OECD criteria.
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