Registration Dossier
Registration Dossier
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 812-378-1 | CAS number: 210420-85-2
Partition coefficient
Administrative data
- Endpoint:
- partition coefficient
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- From 18 November 2016 to 23 March 2017
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
Cross-reference
- Reason / purpose for cross-reference:
- reference to other study
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 017
- Report date:
- 2017
Materials and methods
Test guidelineopen allclose all
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.8 (Partition Coefficient)
- Version / remarks:
- 2008
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 107 (Partition Coefficient (n-octanol / water), Shake Flask Method)
- Version / remarks:
- 1995
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- EPA OPPTS 830.7550 (Partition Coefficient, n-octanol / H2O, Shake Flask Method)
- Version / remarks:
- 1996
- Deviations:
- no
- GLP compliance:
- yes
- Type of method:
- estimation method (solubility ratio)
- Partition coefficient type:
- octanol-water
Test material
- Reference substance name:
- Reference substance 001
- Cas Number:
- 210420-85-2
- Reference substance name:
- N-methyldidecylamine
- EC Number:
- 230-990-1
- EC Name:
- N-methyldidecylamine
- Cas Number:
- 7396-58-9
- Molecular formula:
- C21H45N
- IUPAC Name:
- N-decyl-N-methyldecan-1-amine
- Reference substance name:
- Water
- EC Number:
- 231-791-2
- EC Name:
- Water
- Cas Number:
- 7732-18-5
- Molecular formula:
- H2O
- IUPAC Name:
- Dihydrogen oxide
- Reference substance name:
- Unknown impurities
- Molecular formula:
- Not available
- IUPAC Name:
- Unknown impurities
- Test material form:
- solid
- Details on test material:
- - Appearance: Slightly yellow gel
- Storage conditions: At room temperature; container flushed with nitrogen
Constituent 1
Constituent 2
Constituent 3
impurity 1
- Specific details on test material used for the study:
- the substance is surface active
Results and discussion
Partition coefficientopen allclose all
- Key result
- Type:
- Pow
- Partition coefficient:
- >= 4 100
- Temp.:
- 20 °C
- pH:
- ca. 8
- Type:
- Pow
- Partition coefficient:
- >= 4 200
- Temp.:
- 20 °C
- pH:
- ca. 8
- Remarks on result:
- other: corrected for the water content in the substance
- Key result
- Type:
- log Pow
- Partition coefficient:
- >= 3.6
- Temp.:
- 20 °C
- pH:
- ca. 8
Applicant's summary and conclusion
- Conclusions:
- The Pow of the substance at 20°C was estimated to be = 4.1E03 (log Pow = 3.6).
- Executive summary:
Because the substance is surface active both the HPLC method and the shake-flask method are not applicable. The log Pow of the substance was therefore estimated from the ratio 'n-octanol solubility and critical micelle concentration'. The Pow of the substance at 20°C was estimated to be = 4.1E03 (log Pow = 3.6) in a GLP study according to EC A.8, OECD 107 and OPPTS 830.7550.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
