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EC number: 222-720-6
CAS number: 3586-55-8
The bioconcentrations in aquatic organisms
was estimated according to a QSAR model.
Data on formaldehyde
One recent study on marine fish is
available in which tissue formaldehyde levels after exposure to
formaldehyde were investigated. Elevated formaldehyde levels in muscle
tissue (by 0.8 µg/g wet weight) were found only directly after a
one-hour treatment at 185 mg/L, but not after a 24-hour or longer
depuration period. Assuming that one hour was sufficient to reach
steady-state conditions a BCF of 4 x 10-6 was calculated, however,
reliability of that value has to remain questionable. The study was
conducted to investigate formaldehyde concentrations in fish after
typical antiparasitical treatments in aquaculture, but aimed not at the
determination of a BCF for formaldehyde.
Two older studies are cited in WHO
(2002) and OECD (2002), in which no elevated formaldehyde contents were
found after a one or three–hour treatments at 121 mg/L in marine and
freshwater fish tissue, and after 24 hours of treatment (50 and 150
mg/L) in marine shrimp tissue. Shrimp tail muscle was found to produce
small amounts of formaldehyde during postmortem decomposition.
Additional information on logPow as
well as the estimated BCFfish and biomagnification factor for
fish-eating predators support the experimental findings that
formaldehyde does not bioconcentrate in aquatic biota.
There is no study available on
accumulation of formaldehyde in terrestrial organisms. Therefore, the
BCF for earthworms was estimated according a QSAR model described in EU
Technical Guidance Document on Risk Assessment (EC 2003). As the value
is very low, bioaccumulation potential is not expected for terrestrial
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