Registration Dossier
Registration Dossier
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EC number: 210-275-0 | CAS number: 611-70-1
Short-term toxicity to fish
Administrative data
- Endpoint:
- short-term toxicity to fish
- Type of information:
- experimental study
- Adequacy of study:
- other information
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: Non-GLP guideline study
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 1 989
- Report date:
- 1989
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- other: DIN 38412 part 15
- GLP compliance:
- no
Test material
- Reference substance name:
- Isobutyrophenone
- EC Number:
- 210-275-0
- EC Name:
- Isobutyrophenone
- Cas Number:
- 611-70-1
- Molecular formula:
- C10H12O
- IUPAC Name:
- 2-methyl-1-phenylpropan-1-one
- Details on test material:
- - Name of test material (as cited in study report): Darocur Stufe 1
- Physical state: clear, pale yellow liquid
- Analytical purity: 99.5%
Constituent 1
Sampling and analysis
- Analytical monitoring:
- no
Test solutions
- Vehicle:
- no
Test organisms
- Test organisms (species):
- Leuciscus idus
- Details on test organisms:
- TEST ORGANISM
- Common name: Golden orfe
- Source: Zoo Meyer, Darmstadt, Germany
- Feeding during test: none
Study design
- Test type:
- static
- Water media type:
- freshwater
- Limit test:
- no
- Total exposure duration:
- 48 h
Test conditions
- Test temperature:
- 20 °C
- Nominal and measured concentrations:
- Nominal test concentrations: 20, 30, 40, 50, 75 mg/L
- Details on test conditions:
- TEST SYSTEM
- No. of organisms per vessel: 5
- No. of vessels per concentration (replicates): 1
TEST MEDIUM / WATER PARAMETERS
- Source/preparation of dilution water: synthetic test water according to DIN 38412 part 15
OTHER TEST CONDITIONS
- Illumination: daylight
EFFECT PARAMETERS MEASURED: mortality after 48 hours
Results and discussion
Effect concentrationsopen allclose all
- Duration:
- 48 h
- Dose descriptor:
- LC0
- Effect conc.:
- 30 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mortality (fish)
- Duration:
- 48 h
- Dose descriptor:
- LC50
- Effect conc.:
- 36 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mortality (fish)
- Duration:
- 48 h
- Dose descriptor:
- LC100
- Effect conc.:
- 75 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mortality (fish)
Applicant's summary and conclusion
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
