Registration Dossier

Diss Factsheets

Administrative data

Key value for chemical safety assessment

Genetic toxicity in vitro

Description of key information

Gene mutation of the target4-Chlorobenzenesulfonic acidwas estimated by using the following predictors: Derek Nexus, Sarah Nexus, Vega (four models).The predictors were employed in order to apply a weight of evidence (WoE) approach to enhance the reliability of the prediction. In the weight of evidence assessment only reliable predictions are to be taken into account. In the case of the target 4-Chlorobenzenesulfonic acid, Vega, Derek Nexus and Sarah Nexus were in agreement providing a negative prediction. Therefore, it was concluded that 4-Chlorobenzenesulfonic acid was predicted with a high level of confidence as negative.

Endpoint conclusion
Endpoint conclusion:
no adverse effect observed (negative)

Additional information

Justification for classification or non-classification