Registration Dossier
Registration Dossier
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EC number: 210-412-4 | CAS number: 615-16-7
Endpoint summary
Administrative data
Description of key information
KEY STUDY, OECD 401 (KEY_401_1986_HOECHST_86.0391): LD50 female rat = 1930 mg/kg bw (= most sensitive sex)
NON-KEY STUDY, unspecified guideline (NONKEY-401-2007-MSDS SYNTHESIA): LD50 rat = 1105 mg/kg bw
Key value for chemical safety assessment
Acute toxicity: via oral route
Endpoint conclusion
- Dose descriptor:
- LD50
- Value:
- 1 930 mg/kg bw
Additional information
Testing for acute oral toxicity following OECD standard method revealed LD50 values of 2280 mg/kg bw for male and 1930 mg/kg bw for female rats. The lower value of 1930 mg/kg bw representing the most senitive response was identified to be suitable for classification purpose. Findings of a second supportive study (LD50: 1105 mg/kg bw) only available from a SDS, are not inconsistent with this conclusion.
Justification for classification or non-classification
The derived LD50 value of 1930 mg/kg bw meets criteria for classification as Xn, R 22 or Acute toxicity — Oral, Cat 4, H302.
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