Registration Dossier
Registration Dossier
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EC number: 255-464-9 | CAS number: 41621-49-2
Skin sensitisation
Administrative data
- Endpoint:
- skin sensitisation, other
- Type of information:
- experimental study
- Adequacy of study:
- supporting study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- data from handbook or collection of data
Data source
Reference
- Reference Type:
- publication
- Title:
- SIDS INITIAL ASSESSMENT PROFILE for 2-aminoethanol
- Author:
- OECD
- Year:
- 2 013
- Bibliographic source:
- OECD SIDS INITIAL ASSESSMENT PROFILE
Materials and methods
- Principles of method if other than guideline:
- Data published on sensitizing potential for 2-aminoethanol, neutral form of ethanolaminium cation.
- GLP compliance:
- not specified
In vivo test system
Test animals
- Species:
- other: laboratory animals
Results and discussion
In vivo (non-LLNA)
Results
- Reading:
- other: sensitizing potential
- Remarks on result:
- no indication of skin sensitisation
Applicant's summary and conclusion
- Interpretation of results:
- GHS criteria not met
- Conclusions:
- 2-aminoethanol (MEA) , the neutral form of ethanolminium cation, is not sensitizing in animals. However, available information about MEA in humans is ambiguous as there are negative but also several reports of dermatitis and positive epicutaneous test reactions to MEA.
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