Registration Dossier
Registration Dossier
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EC number: - | CAS number: -
Hydrolysis
Administrative data
- Endpoint:
- hydrolysis
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- other: Guideline study and GLP
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 013
- Report date:
- 2013
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 111 (Hydrolysis as a Function of pH)
- GLP compliance:
- yes (incl. QA statement)
Test material
Constituent 1
Results and discussion
- Transformation products:
- no
Total recovery of test substance (in %)
- % Recovery:
- 82 - 108
Dissipation DT50 of parent compoundopen allclose all
- Key result
- pH:
- 4
- Temp.:
- 20 °C
- Hydrolysis rate constant:
- 2.118 h-1
- DT50:
- 0.3 h
- Key result
- pH:
- 7
- Temp.:
- 20 °C
- Hydrolysis rate constant:
- 0.018 h-1
- DT50:
- 38.7 h
- Key result
- pH:
- 9
- Temp.:
- 20 °C
- Hydrolysis rate constant:
- 0.005 h-1
- DT50:
- 138.6 h
Applicant's summary and conclusion
- Validity criteria fulfilled:
- yes
- Conclusions:
- The test item is hydrolytically unstable at pH4, pH7 and pH9
- Executive summary:
The test item is hydrolytically unstable at pH4, pH7 and pH9
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