Registration Dossier
Registration Dossier
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EC number: 700-585-9 | CAS number: 35786-94-8
Water solubility
Administrative data
- Endpoint:
- water solubility
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- other: GLP- and Guideline Study
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 013
Materials and methods
Test guidelineopen allclose all
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.6 (Water Solubility)
- Qualifier:
- according to guideline
- Guideline:
- EPA OPPTS 830.7840 (Water Solubility)
- GLP compliance:
- yes (incl. QA statement)
- Type of method:
- flask method
Test material
Constituent 1
Results and discussion
Water solubility
- Water solubility:
- ca. 255 mg/L
- Temp.:
- 20 °C
- pH:
- ca. 6.9
Any other information on results incl. tables
FINAL RESULTS
The water solubility CS of the test item was determined at 20°C according to the "flask method"
described in the European Commission Council regulation (EC) No 440/2008. Annex. Part A. A.6.,
OECD-Guideline 105 and the EPA Product Properties Test Guideline OPPTS 830.7840.
The concentrations of the test item were determined by HPLC analysis.
The reversed-phase HPLC method used was found to be valid.
The results of the solubility measurements are shown below:
Solubility in Final pH CS Solubility at 20°C RSD
Double distilled water 6.9 1) 255 * 10 -3 g/L 1.1 %
1) Mean pH – value resulting from three experiments
The sample purity of 98.5 % w/w has been taken into account.
Applicant's summary and conclusion
- Conclusions:
- Interpretation of results (migrated information): moderately soluble (100-1000 mg/L)
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