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Physical & Chemical properties

Water solubility

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Reference
Endpoint:
water solubility
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
other: Study conducted according to internationally accepted testing guidelines.
Reference:
Composition 0
Qualifier:
according to
Guideline:
OECD Guideline 105 (Water Solubility)
GLP compliance:
no
Type of method:
flask method
Test material information:
Composition 1
Water solubility:
119.49 g/L
Temp.:
20 °C
pH:
6
Remarks on result:
other: Average solubility (SD: 2.64)
Details on results:
PRELIMINARY SOLUBILITY RESULT
Reference samples and extract were first measured in the range 190 / 800 nm, so as to choose the right wavelength for quantitative measurements.
Since absorbance of the test solution kept the same proportions along the UV and visible spectra, preliminary test result was considered for the final result calculations. Wavelength chosen was 640.00 nm.

TEST RESULTS
Test 1 (24 hrs): 117.46 g/l
Test 2 (48 hrs): 118.52 g/l
Test 3 (96 hrs): 122.48 g/l

pH mother solution: 6.26
pH of satured solution: 6.00
Conclusions:
Interpretation of results: very soluble (> 10000 mg/L)
Average solubility: 119.49 g/l at 20 °C and pH 6.00
Executive summary:

Solubility was performed following the recommendations of the OECD method 105.

Since absorbance of the test solution kept the same proportions along the UV and visible spectra, preliminary test result was considered for the final results calculations. Wavelength chosen was 640 nm. The water solubility resulted to be 117.46 g/l at 24 hrs, 118.52 g/l at 48 hrs and 122.48 g/l at 96 hrs, at 20 °C and pH 6.00.

Conclusion

Average solubility: 119.49 g/l at 20 °C and pH 6.00.

Description of key information

119.49 g/l at 20 °C and pH 6.00

Key value for chemical safety assessment

Water solubility:
119.49 g/L
at the temperature of:
20 °C

Additional information

Shake Flask method - OECD 105