Registration Dossier
Registration Dossier
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EC number: 201-184-7 | CAS number: 79-19-6
Endpoint summary
Administrative data
Description of key information
Additional information
Short-term toxicity to fish:
Static-96 hr test was conducted to find out the toxicity of thiosemicarbazide to fish. Thiosemicarbazide exposed to Fathead Minnow (Pimephales promelas) at concentration of 20.8mg/L. Fish were observed for 14 days. 50 % mortality was observed at concentration of 20.8 mg/l.Therefore median lethal dose (LC50) was considered to be 20.8 mg/L for Pimephales promelas based on 50% mortality.
Based on the value and biodegradability status, the substance may be classified in aquatic chronic category 3 as per the CLP regulation.
Short-term toxicity to aquatic invertebrates:
Short-term toxicity test to aquatic invertebrates was conducted to study the effects of thiosemicarbazide. The Dose concentration used is 21mg/l for 48 hours. Based on Mortality median lethal dose (LC50) was considered to be 21mg/l for thiosemicarbazide .
Based on the value and biodegradability status, the substance may be classified in aquatic chroniccategory 3 as per the CLP regulation.
Toxicity to aquatic algae and cyanobacteria:
Toxicity test of thiosemicarbazide was done at two concentration 2.8 mg/L and 19 mg/L for 72 h. The EC50 value for thiosemicarbazide is considered to be 19mg/L and the NOEC is 2.8 mg/L.
Based on the value and biodegradability status, the substance may be classified in aquatic chroniccategory 3 as per the CLP regulation.
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