Registration Dossier
Registration Dossier
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EC number: 232-318-2 | CAS number: 8003-22-3 This substance is identified in the Colour Index by Colour Index Constitution Number, C.I. 47000.
Biodegradation in water: screening tests
Administrative data
Link to relevant study record(s)
Description of key information
The BOD28 value of 1,3-isobenzofurandione (CAS No. 8003-22-3) was observed to be 0.0363mgO2/mg. ThoD was determined by calculation as 2.225mgO2/mg. % Degradation was calculated using the values of BOD and ThOD for test item and was found to be 1.63%. The % degradation of procedure control (reference item) was also calculated using BOD & ThOD and was found to be 75.20%.
Key value for chemical safety assessment
- Biodegradation in water:
- under test conditions no biodegradation observed
Additional information
28-days Manometric respirometry test following the OECD guideline 301F to determine the ready biodegradability of the test item 1, 3-isobenzofurandione (CAS No. 8003-22-3). The test system included control, test item and reference item. The concentration of test and reference item (Sodium Benzoate) chosen for both the study was 100mg/L, while that of inoculum was 10ml/l. ThOD (Theoretical oxygen demand) of test and reference item was determined by calculation. % Degradation was calculated using the values of BOD and ThOD for test item and reference item.
The BOD28value of 1, 3-isobenzofurandione (CAS No. 8003-22-3) was observed to be 0.0363 mgO2/mg. ThOD was calculatedas 2.225mgO2/mg. Accordingly, the % degradation of the test item after 28 days of incubation at 20 ± 1°C according to manometric respirometry test was found to be 1.63%. Basedon the results, the test item, under the test conditions, was found to be non-biodegradable at 20 ± 1°C over a period of 28 days.
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