Registration Dossier
Registration Dossier
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EC number: 205-503-0 | CAS number: 141-82-2
Water solubility
Administrative data
Link to relevant study record(s)
- Endpoint:
- water solubility
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- January 2017
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- comparable to guideline study with acceptable restrictions
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.6 (Water Solubility)
- GLP compliance:
- no
- Type of method:
- flask method
- Specific details on test material used for the study:
- Batch number of test material: 20160723
- Key result
- Water solubility:
- 766 g/L
- Conc. based on:
- test mat.
- Temp.:
- 20 °C
- pH:
- < 1
- Conclusions:
- The water solubility of malonic acid is 766 g/L at 20C
- Executive summary:
The water solubility of malonic acid was measured using method A6 Water Solubility (Flask Method). The water solubility was determined to be 766 g/L.
Reference
Flask Test Results:
Test | A | B | C |
Hours stirring | 48 | 48 | 48 |
pH of solution | < 1 | < 1 | < 1 |
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Malonic Acid g/L | 766 | 768 | 766 |
Test Temp. 20oC |
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Solution A from the table above was pH adjusted to 1.5 with hydrochloric acid. Under these conditions there was no decrease in the solubility.
Malonic acid solubility at pH 1.5 = 766 g/L
This method was repeated at different pH to represent possible dissolution in the environment and possible impact on environmental fate and effects.
Solubility between < pH 1 to > pH 10
| Malonic acid g/L |
|
pH < 1 | 766 |
|
pH 1.5 | 766 |
|
pH 4.0 | 766 |
|
pH 7.0 | 766 |
|
pH 9.0 | 766 |
|
pH > 10 | 766 |
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Description of key information
The solubility of malonic acid was determoned using method A6 Water Solubility (Flask Method). The water solubility was determined to be 766 g/L at 20 oC
Key value for chemical safety assessment
- Water solubility:
- 766 g/L
- at the temperature of:
- 20 °C
Additional information
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