Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Hazard for aquatic organisms

Hazard for air

Hazard for terrestrial organisms

Hazard for predators

Additional information

Aquatic toxicity

Two reliable QSAR results are available to assess the aquatic toxicity of the registered substance, on aquatic invertebrates and algae.

The QSAR predictions (iSafeRat holistic approach v1.3) has been validated to be compliant with the OECD recommendations for QSAR modeling (OECD, 2004) and predict the ecotoxicological values which would be expected when testing the substance under experimental conditions in a laboratory following OECD Guidelines. The ecotoxicological predictions were determined using a validated QSAR for the Mode of Action in question, (MOA 1, non-polar narcosis). Use of this MOA for substituted α,β-unsaturated ketones has previously been demonstrated as acceptable in a position paper (KREATiS, 2015; available in the Endpoint Study Records). This QSAR is based on validated data for training sets for which the concentrations of the test substance had been determined by chemical analyses over the test period. According to these predictions, the 48 -EC50 value for aquatic invertebrates, based on mobility, was determined to be 9.5 mg/L (95% CL: 8.7 -10 mg/L), and the 72h-ErC50 value for algae, based on growth rate, was determined to be 8.8 mg/L (95% CL: 7.7 - 10 mg/L). The substance falls within the applicability domain of the model.

Environmental fate and pathways

The registered substance is not readily biodegradable and therefore considered persistent.

Conclusion on classification

No harmonised classification is available.

1 mg/L < lowest EC50 value < 10 mg/L; not readily biodegradable.

Classification according to the Annex VI of the Regulation (EC) No 1272/2008 (CLP): The test substance is classified Aquatic Chronic 2 for the environment.