Registration Dossier
Registration Dossier
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 218-620-7 | CAS number: 2206-94-2
Endpoint summary
Administrative data
Description of key information
The key study for acute oral toxicity, which was conducted according to OECD TG 420 and in compliance with GLP, reports an LD50 value of >2000 mg/kg bw (Hameln, 2015).
Key value for chemical safety assessment
Acute toxicity: via oral route
Endpoint conclusion
- Endpoint conclusion:
- no adverse effect observed
- Dose descriptor:
- LD50
- Value:
- 2 000 mg/kg bw
Additional information
The key study for acute oral toxicity, which was conducted according to OECD TG 420 and in compliance with GLP, reports an LD50 value of >2000 mg/kg bw (Hameln, 2015). One out of four animals died, and there were signs of toxicity including lacrimation, reduced activity, lethargy and mild spasm in hind legs. All animals appeared normal within 48 hours. No macroscopic findings were noted at necropsy.
Justification for selection of acute toxicity – oral endpoint
The study was conducted according to current guideline and in compliance with GLP.
Justification for classification or non-classification
Based on the available data, α-methylenebenzyl acetate does not require classification for acute toxicity according to Regulation (EC) No 1272/2008.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
