Registration Dossier
Registration Dossier
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EC number: 205-003-2 | CAS number: 130-95-0
Short-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
Description of key information
The determined EC50 of quinine sulfate/quinidine sulfate for Daphnia magna is 44.8 mg/L for 24 h and of quinine sulfate 91.93 mg/l for 48 h exposure duration. According to this, the EC50 of quinine/quinidine is 34.4 mg/L (24 h) and of quinine 70.59 mg/L (48 h). The EC50 of quinine hydrochloride for Daphnia pulex is 28.3 mg/L. According to this, the EC50 of quinine is 25.4 mg/L.
Key value for chemical safety assessment
Fresh water invertebrates
Fresh water invertebrates
- Effect concentration:
- 25.4 mg/L
Additional information
In the experimental study published by Guilhermino, 2000 the EC50 of the read across substance quinine sulphate/quinidine sulfate was determined. The EC50 of quinine sulfate for Daphnia magna is 44.8 mg/L for 24 h exposure duration. According to this, the EC50 of quinine is 34.4 mg/L. In the study published by Morrow, 2001 the EC50 of the read across substance quinine hydrochloride for Daphnia pulex was determined with a petri-dish bioassay method and a multiwell bioassay method. The EC50 (24 h) of quinine hydrochloride is 28.3 mg/l. According to this, the EC50 of quinine is 25.4 mg/L.
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