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Physical & Chemical properties

Solubility in organic solvents / fat solubility

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Administrative data

Endpoint:
solubility in organic solvents / fat solubility
Type of information:
experimental study
Adequacy of study:
supporting study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: GLP status not known, guideline not known, information from a published handbook, acceptable with restrictions

Data source

Reference
Reference Type:
review article or handbook
Title:
The Merck Index - An Encyclopedia of Chemicals, Drugs, and Biologicals, 14th edition
Author:
O'Neil MJ (editor)
Year:
2006
Bibliographic source:
Merck Research Laboratories, Merck & Co., Inc. Whitehouse Station, NJ, USA.

Materials and methods

Principles of method if other than guideline:
The use of secondary sources of data is acceptable when they are based on a critical evaluation of peer-reviewed data and a consequent selection of a reliable and representative value for the property under investigation. The introduction to the Merck Index states that physical data are cited as found in the literature. When several alternate data values appear in the literature, the data is evaluated and representative selections are made; values are then reported with the corresponding source. Therefore, although the method used is not known, the values presented here are acceptable as they are from a reliable secondary source of phys chem. data.
GLP compliance:
not specified

Test material

Constituent 1
Reference substance name:
Reference substance 002
Cas Number:
74-84-0
Molecular formula:
C2H6
Details on test material:
No data reported

Results and discussion

Solubility in organic solvents / fat solubility
Medium:
ethanol
Solubility:
460 other: mL/L
Temp.:
4 °C
Test substance stable:
not determined
Details on results:
No data reported

Applicant's summary and conclusion

Conclusions:
Solubility of ethane in alcohol at 4°C is 460 mL/L.
Executive summary:

No information on the primary source of the data or the methods used is available. However, this information is taken from a reliable peer reviewed handbook and so can be considered reliable and suitable for use for this endpoint.