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Endpoint summary

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Description of key information

Key value for chemical safety assessment

Skin sensitisation

Link to relevant study records
Reference
Endpoint:
skin sensitisation: in vitro
Data waiving:
study technically not feasible
Justification for data waiving:
other:
Endpoint conclusion
Endpoint conclusion:
no study available
Additional information:

In accordance with Section 2 of REACH Annex XI, studies on skin sensitisation do not need to be conducted as members and components of the Other Petroleum Gases category are flammable gases at room temperature. No studies have been conducted on skin sensitisation and there are no indications from repeat dose studies or the published literature that any of the gases cause skin sensitisation.


Migrated from Short description of key information:
There are no data on skin sensitisation and no indications that members or main components of Other Petroleum Gases are skin sensitisers. All are flammable gases at room temperature and therefore studies on skin sensitisation are waived.

Justification for selection of skin sensitisation endpoint:
These streams are gases at room temperature, hence testing for skin sensitisation potential is not technically feasible.

Respiratory sensitisation

Link to relevant study records
Reference
Endpoint:
respiratory sensitisation
Data waiving:
other justification
Justification for data waiving:
other:
Endpoint conclusion
Endpoint conclusion:
no study available
Additional information:

No respiratory sensitisation studies have been conducted on members or main components of the Other Petroleum Gases category and there are no indications from other studies to suggest they cause respiratory sensitisation. Furthermore, there is a long history of the commercial use of Other Petroleum Gases and there are no reports from the available literature of respiratory sensitisation. 


Migrated from Short description of key information:
No studies have been conducted but there no indications that members or main components of Other Petroleum Gases are respiratory sensitisers.

Justification for classification or non-classification

There is no indication that members or main components of the Other Petroleum Gases category cause skin or respiratory sensitisation.