Registration Dossier
Registration Dossier
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EC number: 204-262-9 | CAS number: 118-58-1
Endpoint summary
Administrative data
Description of key information
Additional information
Toxicity studies on soil organisms covering invertebrates, micro-organisms and plants have been carried out on the registered substance. The soil toxicity data have been used in the chemical safety assessment to establish PNECsoil.
The observed LC50 from the acute earthworm test (OECD 207) was > 1000 mg/kg soil dw. Chronic or long-term toxicity testing on soil microorganisms (OECD 216) and terrestrial plants (OECD 208 with six species, two monocotyledonous and four dicotyledonous) gave respectively a NOEC of 167mg/kg soil dw and EC10 of 70.5 mg/kg soil dw (tomato, most sensitive species). According to ECHA guidance (Chapter R.7c, section R.7.11.5.3) where data from chronic or long-term tests are available, they should be used in preference to short-term tests to derive the PNEC. Since two long-term NOECs/EC10s are available, the PNEC has been derived from the lowest long-term result of the two trophic levels using, in accordance with ECHA Table R.10-10, an assessment factor of 50 to give a PNECsoil of 1.41 mg/kg soil dw. This value leads to PECsoil/PNEC soil < 1.
Given that the outcome of the chemical safety assessment demonstrates safe use of the substance to the terrestrial compartment, additional long-term testing is not considered to be necessary.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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