Registration Dossier

Diss Factsheets

Administrative data

Description of key information

Non toxic

LD50 oral rat > 5000

LD50 dermal rabbit > 2000

Key value for chemical safety assessment

Acute toxicity: via oral route

Endpoint conclusion
Endpoint conclusion:
no adverse effect observed
Dose descriptor:
LD50
Value:
5 000 mg/kg bw

Acute toxicity: via dermal route

Endpoint conclusion
Endpoint conclusion:
no adverse effect observed
Dose descriptor:
LD50
Value:
2 000 mg/kg bw

Additional information

All studies on the substance and on the category members from primary and secondary literature reported no effect at the tested doses of 2000 or 5000 mg/Kg/bw for both oral and dermal routes. Inhalation route is not relevant based on exposure consideration and physical chemical properties of the substance.

Justification for classification or non-classification

Classification is only relevant for LD50 < 2000 mg/kg from any route of exposure and none of the tests have indicated such a result.

No classification for acute toxicity is warranted under 67/548/EEC or Regulation 1272/2008.