Registration Dossier

Administrative data

Endpoint:
repeated dose toxicity: oral
Type of information:
migrated information: read-across based on grouping of substances (category approach)
Adequacy of study:
supporting study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: GLP compliant, near guideline study, available as unpublished report, fully adequate for assessment

Data source

Materials and methods

Test material

Constituent 1
Chemical structure
Reference substance name:
2-methylpropene
EC Number:
204-066-3
EC Name:
2-methylpropene
Cas Number:
115-11-7
Molecular formula:
C4H8
IUPAC Name:
2-methylprop-1-ene
Constituent 2
Reference substance name:
isobutylene
IUPAC Name:
isobutylene

Results and discussion

Target system / organ toxicity

Critical effects observed:
not specified

Applicant's summary and conclusion