Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Toxicological information

Developmental toxicity / teratogenicity

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Administrative data

Endpoint:
developmental toxicity
Type of information:
read-across from supporting substance (structural analogue or surrogate)
Adequacy of study:
supporting study
Justification for type of information:
The study OECD 421, performed on an analogue substance (AES, Alkaline Earth Silicates, EC 610-130-5), has been evaluated and deemed robust for re-use in the argumentation.
However, we are still in discussion with the LR of the AES in order to get the right to use and sub-licence this study. Within the timeline imposed by ECHA to submit the updated MMVF LR dossier, it is not technically feasible to obtain such rights, pay the corresponding fees and then integrate the study within the dossier. You will find below proof of communication between the AES LR and MMVF LR represented by the consortium consultant SOCOTEC. The elements will be included in the dossier in the next update.

Data source

Materials and methods

Results and discussion

Applicant's summary and conclusion