Registration Dossier

Ecotoxicological information

Endpoint summary

Administrative data

Description of key information

Additional information

Acute Fish Toxicity:

Water accommodated fractions of isomerization naphtha produced a 96-hour LL50 value of 10 mg/L with Oncorhynchus mykiss. Water accommodated fractions of light alkylate naphtha produced a 96-hour LL50 value of 8.2 mg/L with Pimephales promelas. These data are used as read-across to all substances in the naphtha category.

Chronic Fish Toxicity:

Read across has been applied for this endpoint, using the results of long-term toxicity testing on invertebrates (Daphnia). Toxic effects of hydrocarbons are primarily caused by narcosis, and occur in a narrow range of molar concentrations across aquatic taxa; hence, read across between species is justified.

Acute Invertebrate Toxicity:

Water accommodated fractions of light straight-run naphtha produced a 48-hour EL50 value of 4.5 mg/L with Daphnia magna. These data are used as read-across to all substances in the naphtha category.

Chronic Invertebrate Toxicity:

Water accommodated fractions of light alkylate naphtha produced a 21 -day NOELR (No Observed Effect Loading Rate) value of 2.6 mg/L with Daphnia magna. These data are used as read-across to all substances in the naphtha category.

Algal Toxicity:

Water accommodated fractionsof gasoline produced a freshwater 72 -hour EL50 for Selenastrum capricornutum (new name: Pseudokirchnerella subcapitata) of 3.1 mg/L based on growth rate. The 72 -hour NOELR (No Observed Effect Loading Rate) value for Pseudokirchnerella subcapitata is 0.5 mg/L based on growth rate. These data are used as read-across to all substances in the naphtha category.

Microorganism Toxicity:

The estimated 72-hr LL50 value for Tetrahymena pyriformis, one of the most sensitive aquatic microorganism species, is 15.41 mg/L.

Some information for this category has been generated using the models PETROTOX and/or SPARC. The QMRFs for PETROTOX and SPARC are attached in IUCLID Section 13, with the associated QPRF.