Brief Profile

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Please be aware that the REACH registration parts of this Brief Profile are no longer maintained; they remain frozen as of 19th May 2023. All other data parts (substance identity, C&L, key regulatory lists etc. are up to date).

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Brief Profile

The Brief Profile summarizes the non-confidential data on substances as it is held in the databases of the European Chemicals Agency (ECHA), including data provided by third parties. The Brief Profile is automatically generated; note that it does not currently distinguish between harmonised classification and minimum classification; information requirements under different legislative frameworks may therefore not be fully up to date or complete. For accuracy reasons, substance manufacturers and imports have the responsibility to consult official sources, e.g. the electronic edition of the Official Journal of the European Union.
This Brief Profile is covered by the ECHA Legal Notice.

Substance Description

Substance identity

EC / List no.:
265-151-9
CAS no.:
64742-49-0
Index number:
649-328-00-1
Molecular formula:
SMILES:
InChI:
Type of substance:
UVCB
Origin:
Petroleum product
Registered compositions:
33
Of which contain:
0 impurities relevant for classification
0 additives relevant for classification
Substance Listed:
EINECS (European INventory of Existing Commercial chemical Substances) List

Hazard classification & labelling

Danger! According to the harmonised classification and labelling (ATP01) approved by the European Union, this substance may be fatal if swallowed and enters airways, may cause genetic defects and may cause cancer.

Additionally, the classification provided by companies to ECHA in REACH registrations identifies that this substance is toxic to aquatic life with long lasting effects, is an extremely flammable liquid and vapour, is suspected of damaging fertility or the unborn child, causes skin irritation and may cause drowsiness or dizziness.

Additionally, the classification provided by companies to ECHA in CLP notifications identifies that this substance is a highly flammable liquid and vapour and causes serious eye irritation.

Breakdown of all 2762 C&L notifications submitted to ECHA

Asp. Tox. 1 H304 Harmonised Classification
Carc. 1B H350 Harmonised Classification
Muta. 1B H340 Harmonised Classification
STOT SE 3 H336
Aquatic Chronic 2 H411
Skin Irrit. 2 H315
Flam. Liq. 2 H225
Repr. 2 H361f
Flam. Liq. 3 H226
Flam. Liq. 1 H224
Eye Irrit. 2 H319
Aquatic Chronic 3 H412
STOT RE 1 H372
Acute Tox. 4 H332
STOT RE 2 H373
https://echa.europa.eu/o/diss-blank-theme/images/cnl/graph/more.png 0% 10% 20% 30% 40% 50% 60% 70% 80% 90% 100%

https://echa.europa.eu/o/diss-blank-theme/images/cnl/graph/tick.png Harmonised Classification

https://echa.europa.eu/o/diss-blank-theme/images/cnl/graph/Reach.png REACH registration dossiers notifications

https://echa.europa.eu/o/diss-blank-theme/images/cnl/graph/CLP.png CLP notifications

At least one notifier has indicated that an impurity or an additive present in the substance impacts the notified classification.

Properties of concern

  • C
Officially recognised in the EU as Carcinogenic (Harmonised C&L).
  • C
There is no overall agreement among data submitters, but a minority indicate they consider this substance as Carcinogenic (2.38% of REACH registrations).
  • M
Officially recognised in the EU as Mutagenic (Harmonised C&L).
  • M
There is no overall agreement among data submitters, but a minority indicate they consider this substance as Mutagenic (1.43% of REACH registrations).

Regulatory context

Registration, Evaluation, Authorisation & Restriction of Chemicals (REACH)

Registration
Pre-registration:
Substance pre-registered under REACH.
Registration:
This substance has 31 active registrations under REACH, 1 Joint Submission(s) and 0 Individual Submission(s).
Please see Registrants/Suppliers details.
Evaluation
Dossier Evaluation:
Substance Evaluation:
Authorisation
Candidate List:
Annex XIV (Authorisation List):
Restriction
Annex XVII (Restriction List):

Persistent Organic Pollutants Regulation (POPs)

List of substances subject to the POPs Regulation:
List of substances proposed as POPs:

Classification Labelling & Packaging (CLP)

Harmonised C&L:
A European Union Harmonised Classification & Labelling has been assigned to this substance.
Seveso Annex I:
Notified C&L:
Classification & Labelling has been notified by industry to ECHA for this substance.

Biocidal Products Regulation (BPR)

Active Substance:
Biocidal Products:

Prior Informed Consent (PIC)

Annex I:
Annex V:

European Union Observatory for Nanomaterials (EUON)

EUON:

About this substance

This substance is registered under the REACH Regulation and is manufactured in and / or imported to the European Economic Area, at ≥ 1 000 000 to < 10 000 000 tonnes per annum.

This substance is used by consumers, in articles, by professional workers (widespread uses), in formulation or re-packing, at industrial sites and in manufacturing.

This substance is used in the following products: fuels, air care products, anti-freeze products, coating products, lubricants and greases, washing & cleaning products and welding & soldering products.

Other release to the environment of this substance is likely to occur from: indoor use in close systems with minimal release (e.g. cooling liquids in refrigerators, oil-based electric heaters), outdoor use in close systems with minimal release (e.g. hydraulic liquids in automotive suspension, lubricants in motor oil and break fluids), indoor use as processing aid and outdoor use as processing aid.

This substance is used in the following activities or processes at workplace: production of mixtures or articles by tabletting, compression, extrusion or pelletisation and the low energy manipulation of substances bound in materials or articles.

Release to the environment of this substance can occur from industrial use: in processing aids at industrial sites, manufacturing of the substance, formulation of mixtures, as an intermediate step in further manufacturing of another substance (use of intermediates), as processing aid and of substances in closed systems with minimal release.

This substance can be found in products with material based on: rubber (e.g. tyres, shoes, toys).

ECHA has no public registered data indicating whether or in which chemical products the substance might be used.

ECHA has no public registered data on the types of manufacture using this substance.

This substance is used in the following activities or processes at workplace: transfer of chemicals, closed processes with no likelihood of exposure, closed, continuous processes with occasional controlled exposure and closed batch processing in synthesis or formulation.

Other release to the environment of this substance is likely to occur from: indoor use in close systems with minimal release (e.g. cooling liquids in refrigerators, oil-based electric heaters), outdoor use in close systems with minimal release (e.g. hydraulic liquids in automotive suspension, lubricants in motor oil and break fluids), indoor use as processing aid and outdoor use as processing aid.

ECHA has no public registered data indicating whether or in which chemical products the substance might be used.

This substance is used in the following activities or processes at workplace: transfer of chemicals, closed processes with no likelihood of exposure, closed, continuous processes with occasional controlled exposure, closed batch processing in synthesis or formulation and laboratory work.

Release to the environment of this substance can occur from industrial use: formulation of mixtures, manufacturing of the substance, formulation in materials, in processing aids at industrial sites, in the production of articles, as an intermediate step in further manufacturing of another substance (use of intermediates), as processing aid, for thermoplastic manufacture, as processing aid and of substances in closed systems with minimal release.

This substance has an industrial use resulting in manufacture of another substance (use of intermediates).

This substance is used in the following areas: formulation of mixtures and/or re-packaging. This substance is used for the manufacture of: chemicals and rubber products.

This substance is used in the following activities or processes at workplace: transfer of chemicals, closed processes with no likelihood of exposure, closed, continuous processes with occasional controlled exposure, closed batch processing in synthesis or formulation and laboratory work.

Release to the environment of this substance can occur from industrial use: in processing aids at industrial sites, as an intermediate step in further manufacturing of another substance (use of intermediates), of substances in closed systems with minimal release, as processing aid, manufacturing of the substance, formulation of mixtures, in the production of articles, as processing aid and for thermoplastic manufacture.

This substance is used in the following activities or processes at workplace: transfer of chemicals, closed processes with no likelihood of exposure, laboratory work, closed, continuous processes with occasional controlled exposure and closed batch processing in synthesis or formulation.

Release to the environment of this substance can occur from industrial use: manufacturing of the substance, in processing aids at industrial sites and as processing aid.

Precautions for using this substance have been recommended by its registrants under REACH, as follows:

Prevention statements

When handling this substance: obtain special instructions before use; keep away from heat, sparks, open flames and/or hot surfaces – No smoking; avoid release to the environment; wear protective gloves and/or clothing, and eye and/or face protection as specified by manufacturer/supplier.

Response statements

In case of incident: If swallowed: immediately call a poison center or doctor/physician. Do not induce vomiting.

Storage statements

Store this substance in a well-ventilated place and keeping container tightly closed.

Guidance on the safe use of the substance provided by manufacturers and importers of this substance.

Registrants/suppliers

  • BAYERNOIL Raffineriegesellschaft mbH, Raffineriestr. 100 93333 Neustadt Bavaria Germany
  • CHEMICAL INSPECTION & REGULATION SERVICE LIMITED, Regus Harcourt Centre D02 HW77 Dublin Ireland
  • Crossbridge Energy A/S, Egeskovvej 265 7000 Fredericia Denmark
  • Delrin Netherlands B.V., Baanhoekweg 22 3313 Dordrecht Netherlands
  • Elektronica SM Handels GmbH, Mergenthalerstr. 31 48268 Greven NRW Germany
  • Esso Raffinage S.A.S., 20 Rue Paul Heroult 92000 Nanterre France
  • ExxonMobil Petroleum & Chemical BV, Polderdijkweg 2030 Antwerpen Belgium
  • Hellenic Petroleum R.S.S.O.P.P. S.A., 8A Chimarras street 15125 Marousi Attica Greece
  • Holborn Europa Raffinerie GmbH, Moorburger Strasse 18 21079 Hamburg Germany
  • Intertek Deutschland GmbH_UKEO2019, Stangenstr.1 70771 Leinfelden- Echterdingen Germany
  • INTERTEK FRANCE, ZAC Ecoparc II 27400 HEUDEBOUVILLE France
  • Kalundborg Refinery A/S, Melbyvej 10 4400 Kalundborg Denmark
  • Labcorp Development SA 067, Parque Empresarial Las Tablas, Edificio 1 Calle Federico Mompou, 5 – 5 Planta 28050 Madrid Spain
  • MOTOR OIL (HELLAS) CORINTH REFINERIES S.A., Irodou Attikou 12a 15124 Marousi Athens Greece
  • Neste Oyj, Keilaranta 21 FI-02150 Espoo Finland
  • NWL FRANCE SERVICES, 738, rue Yves Kermen 92100 Boulogne Billancourt France France
  • NWL ITALY S.R.L, Via Ugo Bassi 21 20159 Milan Italy Italy
  • OMV Downstream GmbH, Trabrennstraße 6-8 A-1020 Wien Austria
  • Petroleos del Norte, S.A., Ed. Muñatones, Bº San Martín, 5 48550 Muskiz Vizcaya Spain
  • Raffinerie Heide GmbH, Meldorfer Straße 43 25770 Hemmingstedt Germany
  • Rafineria Gdańska Sp. z o.o., Elbląska 135 80-718 Gdańsk Poland
  • Ramboll Deutschland GmbH, Werinherstraße 79 Gebäude 32a 81541 München Germany
  • REACHLaw Ltd., Aleksanterinkatu 19 00100 Helsinki Finland
  • Repsol Petroleo, S.A., Calle Mendez Alvaro, 44 28045 Madrid Madrid Spain
  • SARPOM S.r.l., Viale Castello della Magliana 25 00148 Roma Italy
  • SC Rompetrol Rafinare SA, Navodari Street no.215, Administrative Building 905700 Navodari Constanta Romania
  • Shell Deutschland GmbH, Suhrenkamp 71-77, 22335 Hamburg Germany
  • Shell Nederland Raffinaderij B.V., Vondelingenweg 601 Postbus 3000 3190 GA Rotterdam Netherlands Netherlands
  • St1 Refinery AB, Bensinvägen 10 PO.Box 8889 402 72 Göteborg Göteborg Sweden
  • TotalEnergies Fluids, 2 Place Jean Millier 92078 PARIS La Défense Cedex France
  • TotalEnergies Raffinage France, 2, place Jean Millier, La Défense 92400 Courbevoie France
  • Basell Polyoléfines France SAS, Chemin Departemental 21 A 13130 Berre l'Etang France
  • Borealis AG, Trabrennstrasse 6-8 1020 Wien Austria
  • Esso Norge AS, Grenseveien 6 4313 Sandnes Norway
  • Esso Petroleum Company Ltd., Ermyn Way ExxonMobil House KT22 8UX Surrey Leatherhead United Kingdom
  • IES - Italiana Energia e Servizi S.p.A., Strada Cipata, 79 46100 Mantova Lombardia Italy
  • Lanxess Deutschland GmbH, Kennedyplatz 1 50569 Köln Germany
  • OMV PETROM S.A., 22 Coralilor Street (“Petrom City”) Sector 1 013329 Bucharest Romania
  • Petrobras Global Trading B.V., Weena 798C – 23rd floor 3014 DA Rotterdam Netherlands
  • PETROBRAS GLOBAL TRADING BV - PGT BV, Weena 798C – 23rd floor First Rotterdam 3014 DA Rotterdam Netherlands

Substance names and other identifiers

Hydrocarbons, C6, isoalkanes, <5% n-hexane
A complex combination of hydrocarbons obtained by treating a petroleum fraction with hydrogen in the presence of a catalyst. It consists of hydrocarbons having carbon numbers predominantly in the range of C4 through C11 and boiling in the range of approximately minus 20°C to 190°C (-4°F to 374°F).
Other
Hydrotreated light straight run (petroleum)
A complex combination of hydrocarbons obtained by treating a petroleum fraction with hydrogen in the presence of a catalyst. It consists of hydrocarbons having carbon numbers predominantly in the range of C4 through C11 and boiling in the range of approximately minus 20°C to 190°C (-4°F to 374°F).
Other
Naphtha (petroleum), hydrotreated light
EC Inventory, Other, Cosmetic Products Regulation, Annex II - Prohibited Substances
Naphtha (petroleum), hydrotreated light
A complex combination of hydrocarbons obtained by treating a petroleum fraction with hydrogen in the presence of a catalyst. It consists of hydrocarbons having carbon numbers predominantly in the range of C4 through C11 and boiling in the range of approximately minus 20°C to 190°C (-4°F to 374°F).
REACH pre-registration, Other, Cosmetic Products Regulation, Annex II - Prohibited Substances
Naphtha (petroleum), hydrotreated light; Low boiling point hydrogen treated naphtha [ complex combination of hydrocarbons obtained by treating a petroleum fraction With hydrogen in the presence of a catalyst. It consists of hydrocarbons having carbon numbers predominantly in the range of C4 through C11 and boiling in the range of approximately minus 20o C to 190o C (- 4°F to 374°F).]
A complex combination of hydrocarbons obtained by treating a petroleum fraction with hydrogen in the presence of a catalyst. It consists of hydrocarbons having carbon numbers predominantly in the range of C4 through C11 and boiling in the range of approximately minus 20°C to 190°C (-4°F to 374°F).
Active Implantable Medical Devices Directive - Hazardous Substances, In Vitro Diagnostic Medical Devices Directive - Hazardous Substances, Medical Devices Directive - Hazardous Substances
Naphtha (petroleum), hydrotreated light; Low boiling point hydrogen treated naphtha [A complex combination of hydrocarbons obtained by treating a petroleum fraction With hydrogen in the presence of a catalyst. It consists of hydrocarbons having carbon numbers predominantly in the range of C4 through C11 and boiling in the range of approximately minus 20o C to 190o C (- 4°F to 374°F).]
A complex combination of hydrocarbons obtained by treating a petroleum fraction with hydrogen in the presence of a catalyst. It consists of hydrocarbons having carbon numbers predominantly in the range of C4 through C11 and boiling in the range of approximately minus 20°C to 190°C (-4°F to 374°F).
FCM Active and Intelligent Materials - CMRs not allowed for use, CAD - Chemical Agents Directive, Art. 2(b)(i) - Hazardous Agents, Construction Product Regulation - Annex I (3) - Hazardous Substances, Construction Product Regulation - Art. 6(5) - SDS and Declaration, EU Ecolabels - Restrictions for Hazardous Substances/Mixtures, End-of-Life Vehicles Directive - Hazardous Substances, In Vitro Diagnostic Medical Devices Regulation - Hazardous Substances, Marine Environmental Policy Framework Directive - Hazardous Substances, Medical Devices Regulation - Hazardous Substances, Protection of Pregnant and Breastfeeding Workers Directive, Annex I+II, General Product Safety Directive - Hazardous Substances, Workplace Signs - minimum requirements & signs on containers and pipes, Safety and Health of Workers at Work Directive - Hazardous Substances, Waste Framework Directive, Annex III - Waste - Hazardous Properties, Carc and Muta Directive, Annex I - Substances, Mixtures & Processes, Physical, Biological and Chemical Agents & Processes and Work
Naphtha, petroleum, hydrotreated light
A complex combination of hydrocarbons obtained by treating a petroleum fraction with hydrogen in the presence of a catalyst. It consists of hydrocarbons having carbon numbers predominantly in the range of C4 through C11 and boiling in the range of approximately minus 20°C to 190°C (-4°F to 374°F).
Other
Fracţia nafta (petrol), fracţiune uşoară hidrotratată Nafta cu punct de fierbere scăzut tratată cu hidrogen [O combinaţie complexă de hidrocarburi obţinute prin tratarea unei fracţiuni de petrol cu hidrogen în prezenţa unui catalizator. Constă cu precădere în hidrocarburi al căror număr de atomi de carbon variază în principal între C4 şi C11, şi al căror punct de fierbere este cuprins între aproximativ –20°C şi 190°C (-4°F şi 374°F).] (ro)
C&L Inventory
Fracţia nafta (petrol), fracţiune uşoară hidrotratată Nafta cu punct de fierbere scăzut tratată cu hidrogen O combinaţie complexă de hidrocarburi obţinute prin tratarea unei fracţiuni de petrol cu hidrogen în prezenţa unui catalizator. Constă cu precădere în hidrocarburi al căror număr de atomi de carbon variază în principal între C4 şi C11, şi al căror punct de fierbere este cuprins între aproximativ –20°C şi 190°C (-4°F şi 374°F). (mt)
C&L Inventory
[A complex combination of hydrocarbons obtained by treating a petroleum fraction with hydrogen in the presence of a catalyst. It consists of hydrocarbons having carbon ...
C&L Inventory
A complex combination of hydrocarbons obtained by treating a petroleum fraction with hydrogen in the presence of a catalyst. It consists of hydrocarbons having carbon numbers predominantly in the range of C4 through C11 and boiling in the range of approximately minus 20°C to 190°C (-4°F to 374°F).
C&L Inventory
Benzínové frakce (ropná)
C&L Inventory
Heptane
Registration dossier
Hydrocarbon
C&L Inventory
Low boiling point hydrogen treated naphtha
C&L Inventory
n-Hexan, Karbochem Hexane, EXXSOL DHN, Exxsol hexane
Registration dossier
nafta (petrolio), hydrotreated light (benzene<0.1)
C&L Inventory
naphta (petroleum), hydrotreated light
C&L Inventory
Naphtha
C&L Inventory
Naphtha (petroleum)
C&L Inventory
Naphtha (petroleum), hyd retreated light
C&L Inventory
NAPHTHA (PETROLEUM), HYDROTREATED LIGHT
C&L Inventory, Registration dossier
Naphtha (petroleum), hydrotreated light
C&L Inventory, Registration dossier
Naphtha (petroleum), hydrotreated light (benzene <0.1%)
C&L Inventory
Naphtha (petroleum), hydrotreated light; Low boiling point hydrogen treated naphtha
C&L Inventory
Naphtha (petroleum), hydrotreated light; Low boiling point hydrogen treated naphtha; [A complex combination of hydrocarbons obtained by treating a petroleum fraction with hydrogen in the presence of a catalyst. It consists of hydrocarbons having carbon numbers predominantly in the range of C4 through C11 and boiling in the range of approximately minus 20°C to 190 °C (-4°F to 374°F).]
C&L Inventory
Naphtha, petroleum, hydrotreated light
C&L Inventory
Naptha petroleum hydrotreated (light)
Registration dossier
Petroleum ether
C&L Inventory
Petroleum hydrocarbon solvent
Registration dossier
Reaction mass of 3-methylpentane and methylcyclopentane and 2-methylpentane and n-hexane and cyclohexane
C&L Inventory
Chem Feed Naphtha
Registration dossier
Isomerisation feed
Registration dossier
LSR
Registration dossier
Naphtha
Registration dossier
Naphtha (petroleum), hydrotreated light
Registration dossier
PETROSOLVE INTERMEDIARIO
Registration dossier
Reference standards, R+D chemicals
C&L Inventory
Special Naphtholite 66/3
Registration dossier
Tops
Registration dossier
64742-49-0
CAS number
EC Inventory, C&L Inventory, Registration dossier, REACH pre-registration, Other, FCM Active and Intelligent Materials - CMRs not allowed for use, CAD - Chemical Agents Directive, Art. 2(b)(i) - Hazardous Agents, Construction Product Regulation - Annex I (3) - Hazardous Substances, Construction Product Regulation - Art. 6(5) - SDS and Declaration, Cosmetic Products Regulation, Annex II - Prohibited Substances, EU Ecolabels - Restrictions for Hazardous Substances/Mixtures, End-of-Life Vehicles Directive - Hazardous Substances, Active Implantable Medical Devices Directive - Hazardous Substances, In Vitro Diagnostic Medical Devices Directive - Hazardous Substances, In Vitro Diagnostic Medical Devices Regulation - Hazardous Substances, Marine Environmental Policy Framework Directive - Hazardous Substances, Medical Devices Directive - Hazardous Substances, Medical Devices Regulation - Hazardous Substances, Protection of Pregnant and Breastfeeding Workers Directive, Annex I+II, General Product Safety Directive - Hazardous Substances, Workplace Signs - minimum requirements & signs on containers and pipes, Safety and Health of Workers at Work Directive - Hazardous Substances, Waste Framework Directive, Annex III - Waste - Hazardous Properties, Carc and Muta Directive, Annex I - Substances, Mixtures & Processes, Physical, Biological and Chemical Agents & Processes and Work
649-328-00-1
Index number
C&L Inventory

Scientific properties

Physical and chemical properties

This section provides physicochemical information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Appearance/physical state / colour

Study results
  • 2 studies submitted
  • 2 studies processed
C Physical state at 20°C and 1013 hPa
Liquid (100%) [2]
C Form
Other (100%) [2]
C Substance type
Petroleum product (100%) [2]

Type of Study provided
Studies with data
Key study 2
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Melting/freezing point

Study results
  • 2 studies submitted
  • 2 studies processed
R Melting / freezing point
-60 °C [2]

Type of Study provided
Studies with data
Key study 2
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Boiling point

Study results
  • 4 studies submitted
  • 2 studies processed
R Boiling point
-20 - 260 °C @ 101.325 kPa [2]

Type of Study provided
Studies with data
Key study 2
Supporting study 2
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Density

Study results
  • 2 studies submitted
  • 2 studies processed
R Relative density
0.62 - 0.88 @ 15 °C [2]

Type of Study provided
Studies with data
Key study 2
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Vapour pressure

Study results
  • 2 studies submitted
  • 2 studies processed
R Vapour pressure
240 kPa @ 37.8 °C [2]

Type of Study provided
Studies with data
Key study 2
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Partition coefficient

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study 2
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Water solubility

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study 2
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Solubility in organic solvents / fat solubility

Data not provided by the registrant

Surface tension

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 2
Exposure cons.
Other
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Flash point

Study results
  • 2 studies submitted
  • 2 studies processed
R Flash point
-40 °C [2]

Type of Study provided
Studies with data
Key study 2
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Auto flammability

Study results
  • 8 studies submitted
  • 3 studies processed
R Autoflammability / self-ignition
280 - 470 °C @ 101.3 - 101.325 kPa [3]

Type of Study provided
Studies with data
Key study 2 1
Supporting study 4 1
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Flammability

Study results
  • 2 studies submitted
  • 2 studies processed
C Interpretation of results
Extremely flammable (100%) [2]

Type of Study provided
Studies with data
Key study 2
Supporting study
Weight of evidence
Other
Data waiving
no waivers
C Summaries
  • 2 summaries submitted
  • 2 summaries processed
Flammability
Extremely flammable (100%)

Explosiveness

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 2
Exposure cons.
Other
C Summaries
  • 2 summaries submitted
  • 2 summaries processed
Explosiveness
Non-explosive (100%)

Oxidising

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 2
Exposure cons.
Other
C Summaries
  • 2 summaries submitted
  • 2 summaries processed
Oxidising
No (100%)

Oxidation reduction potential

Data not provided by the registrant

pH

Data not provided by the registrant

Dissociation constant

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible 2
Sci. unjustified
Exposure cons.
Other
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Viscosity

Study results
  • 4 studies submitted
  • 2 studies processed
R kinematic viscosity (in mm²/s)
1 [2]

Type of Study provided
Studies with data
Key study 2
Supporting study 2
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Environmental fate and pathways

This section provides environmental fate and pathways information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Phototransformation in air

Study results
  • 0 studies submitted
  • 0 studies processed

No data available

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Hydrolysis

Study results
  • 4 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study
Supporting study 2
Weight of evidence
Other
Data waiving
Not feasible 2
Sci. unjustified
Exposure cons.
Other
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Phototransformation in water

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 2
Exposure cons.
Other
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Phototransformation in soil

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 2
Exposure cons.
Other
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Biodegradation in water - screening tests

Study results
  • 14 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study 2
Supporting study 12
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Biodegradation in water & sediment - simulation tests

Study results
  • 0 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Biodegradation in soil

Study results
  • 2 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study 2
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Bioaccumulation: aquatic / sediment

Study results
  • 4 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study 4
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Bioaccumulation: terrestrial

Data not provided by the registrant

Adsorption/desorption

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study 2
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Henrys law constant (H)

Data not provided by the registrant

Distribution modelling

Data not provided by the registrant

Ecotoxicological information

This section provides ecotoxicological information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Predicted No-Effect Concentration (PNEC)

R Summaries
  • 2 summaries submitted
  • 2 summaries processed

The Predicted No-Effect Concentration (PNEC) value is the concentration of a substance below which adverse effects in the environment are not expected to occur. Please note that when more than one summary is provided, PNEC values may refer to constituents of the substance and not to the substance as a whole. More detailed information is available in the dossiers.

Hazard for Aquatic Organisms
Freshwater No data available: testing technically not feasible (2)
Intermittent releases (freshwater) No data available: testing technically not feasible (2)
Marine water No data available: testing technically not feasible (2)
Intermittent releases (marine water) No data available: testing technically not feasible (2)
Sewage treatment plant (STP) No data available: testing technically not feasible (2)
Sediment (freshwater) No data available: testing technically not feasible (2)
Sediment (marine water) No data available: testing technically not feasible (2)
Hazard for Air
Air No hazard identified (2)
Hazard for Terrestrial Organism
Soil No data available: testing technically not feasible (2)
Hazard for Predators
Secondary poisoning Insufficient hazard data available (further information necessary) (2)

Short–term toxicity to fish

Study results
  • 32 studies submitted
  • 4 studies processed
P/RResults
LL50 (4 days) 8.2 - 10 mg/L [4]

Type of Study provided
Studies with data
Key study 4
Supporting study 28
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Long–term toxicity to fish

Study results
  • 4 studies submitted
  • 2 studies processed
P/RResults
EL50 (21 days) 10 mg/L [2]
NOELR (21 days) 2.6 mg/L [2]

Type of Study provided
Studies with data
Key study 2
Supporting study 2
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Short–term toxicity to aquatic invertebrates

Study results
  • 24 studies submitted
  • 2 studies processed
P/RResults
EL50 (48 h) 4.5 mg/L [2]
NOELR (48 h) 500 µg/L [2]

Type of Study provided
Studies with data
Key study 2
Supporting study 22
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Long–term toxicity to aquatic invertebrates

Study results
  • 6 studies submitted
  • 2 studies processed
P/RResults
NOELR (21 days) 2.6 - 16 mg/L [4]
EL50 (21 days) 10 - 40 mg/L [4]

Type of Study provided
Studies with data
Key study 2
Supporting study 4
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to aquatic algae and cyanobacteria

Study results
  • 32 studies submitted
  • 2 studies processed
P/RResults
EL50 (4 days) 3.7 mg/L [2]
EL50 (72 h) 3.1 mg/L [2]
NOELR (72 h) 500 µg/L [2]

Type of Study provided
Studies with data
Key study 2
Supporting study 30
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to aquatic plants other than algae

Data not provided by the registrant

Toxicity to microorganisms

Study results
  • 2 studies submitted
  • 2 studies processed
P/RResults
EC50 (40 h) 15.41 mg/L [2]

Type of Study provided
Studies with data
Key study 2
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Sediment toxicity

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible 2
Sci. unjustified
Exposure cons.
Other
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Endocrine disrupter testing in aquatic vertebrates – in vivo

Data not provided by the registrant

Toxicity to terrestrial macroorganisms except arthropods

Study results
  • 4 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study 2
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 2
Exposure cons.
Other
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to terrestrial arthropods

Study results
  • 4 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study 2
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 2
Exposure cons.
Other
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to terrestrial plants

Study results
  • 4 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study 2
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 2
Exposure cons.
Other
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to soil microorganisms

Study results
  • 4 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study 2
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 2
Exposure cons.
Other
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to birds

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 2
Exposure cons.
Other
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to mammals

Data not provided by the registrant

Toxicological information

This section provides toxicological information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Derived No- or Minimal Effect Level (DN(M)EL)

M/C Summaries
  • 4 summaries submitted
  • 4 summaries processed

The derived no- or minimum effect level (DN(M)EL) is the level of exposure above which a human should not be exposed to a substance. Please note that when more than one summary is provided, DN(M)EL values may refer to constituents of the substance and not to the substance as a whole. More detailed information is available in the dossiers.

Data for WORKERS
INHALATION Exposure Threshold Most sensitive study
Systemic Effects
Long-term: (DNEL) 1.9 mg/m³ repeated dose toxicity
Acute /short term: (DNEL) 1 286.4 mg/m³ neurotoxicity
Local Effects
Long-term: (DNEL) 837.5 mg/m³ irritation (respiratory tract)
Acute /short term: (DNEL) 1 066.67 mg/m³ irritation (respiratory tract)
DERMAL Exposure Threshold Most sensitive study
Systemic Effects
Long-term: High hazard (no threshold derived)
Acute /short term: High hazard (no threshold derived)
Local Effects
Long-term: High hazard (no threshold derived)
Acute /short term: Low hazard (no threshold derived)
EYE Exposure
No hazard identified
Data for the GENERAL POPULATION
INHALATION Exposure Threshold Most sensitive study
Systemic Effects
Long-term: (DNEL) 410 µg/m³ repeated dose toxicity
Acute /short term: (DNEL) 1 152 mg/m³ neurotoxicity
Local Effects
Long-term: (DNEL) 178.57 mg/m³ irritation (respiratory tract)
Acute /short term: (DNEL) 640 mg/m³ irritation (respiratory tract)
DERMAL Exposure Threshold Most sensitive study
Systemic Effects
Long-term: High hazard (no threshold derived)
Acute /short term: High hazard (no threshold derived)
Local Effects
Long-term: High hazard (no threshold derived)
Acute /short term: Low hazard (no threshold derived)
ORAL Exposure Threshold Most sensitive study
Systemic Effects
Long-term: No hazard identified
Acute /short term: No hazard identified
EYE Exposure
No hazard identified

Toxicokinetics, metabolism, and distribution

Study results
Study data: basic toxicokinetics
  • 2 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: basic toxicokinetics
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 2
Study data: dermal absorption
  • 0 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: dermal absorption
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Acute toxicity

Study results
oral
  • 86 studies submitted
  • 2 studies processed
P/RResults
LD50 5 000 mg/kg bw (rat) [2]
M/CInterpretations of results
Not classified [2]

Type of Study provided
oral
Studies with data
Key study 2
Supporting study 4 80
Weight of evidence
Other
Data waiving
no waivers
inhalation
  • 78 studies submitted
  • 2 studies processed
M/CInterpretations of results
Not classified [2]

inhalation
Studies with data
Key study 2
Supporting study 76
Weight of evidence
Other
Data waiving
no waivers
dermal
  • 88 studies submitted
  • 2 studies processed
P/RResults
LD50 2 000 mg/kg bw (rabbit) [2]
M/CInterpretations of results
Not classified [2]

dermal
Studies with data
Key study 2
Supporting study 86
Weight of evidence
Other
Data waiving
no waivers
other routes
  • 0 studies submitted
  • 0 studies processed

No data available

other routes
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
M/C Summaries
  • 2 summaries submitted
  • 2 summaries processed
Oral route:
No adverse effect observed LD50 5 000 mg/kg bw
Inhalation route:
No adverse effect observed LC50 5.61 mg/L air
Dermal route:
No adverse effect observed LD50 2 000 mg/kg bw

Irritation / corrosion

Study results
Study data: skin
  • 190 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: skin
Studies with data
Key study 2
Supporting study 6 180
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 2
Exposure cons.
Other
Study data: eye
  • 90 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: eye
Studies with data
Key study 2
Supporting study 86
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 2
Exposure cons.
Other
M/C Summaries
  • 2 summaries submitted
  • 2 summaries processed
Skin
Adverse effect observed (irritating)
Eye
No adverse effect observed (not irritating)
Respiratory
No study available

Sensitisation

Study results
Study data: skin
  • 86 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: skin
Studies with data
Key study 2
Supporting study 82
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 2
Exposure cons.
Other
Study data: respiratory
  • 0 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: respiratory
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
M/C Summaries
  • 2 summaries submitted
  • 2 summaries processed
Skin sensitisation
No adverse effect observed (not sensitising)
Respiratory sensitisation
No study available

Repeated dose toxicity

Study results
Study data: oral
  • 10 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Study data: oral
Studies with data
Key study 2
Supporting study 8
Weight of evidence
Other
Data waiving
no waivers
Study data: inhalation
  • 44 studies submitted
  • 2 studies processed
P/RResults
NOAEC (other:): 1.402 mg/L air [2]

Study data: inhalation
Studies with data
Key study 2
Supporting study 42
Weight of evidence
Other
Data waiving
no waivers
Study data: dermal
  • 100 studies submitted
  • 0 studies processed

No automatically processable data submitted

Study data: dermal
Studies with data
Key study 2
Supporting study 98
Weight of evidence
Other
Data waiving
no waivers
M/C Summaries
  • 2 summaries submitted
  • 2 summaries processed
Inhalation route - systemic effects:
No adverse effect observed NOAEC 1 402 mg/m³ (chronic, rat)

Genetic toxicity

Study results
Study data: in vitro
  • 44 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: in vitro
Studies with data
Key study 6
Supporting study 36
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 2
Exposure cons.
Other
Study data: in vivo
  • 28 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: in vivo
Studies with data
Key study 2
Supporting study 26
Weight of evidence
Other
Data waiving
no waivers
M/C Summaries
  • 2 summaries submitted
  • 2 summaries processed
Toxicity - InVivo
No adverse effect observed (negative)

Carcinogenicity

Study results
  • 24 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study 4
Supporting study 4 16
Weight of evidence
Other
Data waiving
no waivers
M/C Summaries
  • 2 summaries submitted
  • 2 summaries processed
Inhalation route:
No adverse effect observed NOAEC 9 869 mg/m³ (chronic, rat)

Toxicity to reproduction

Study results
Study data: reproduction
  • 8 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: reproduction
Studies with data
Key study 2
Supporting study 6
Weight of evidence
Other
Data waiving
no waivers
Study data: developmental
  • 18 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: developmental
Studies with data
Key study 4
Supporting study 12
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 2
Exposure cons.
Other
Study data: other studies
  • 0 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: other studies
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
M/C Summaries
  • 2 summaries submitted
  • 2 summaries processed
Effect on fertility
Inhalation route:
No adverse effect observed NOAEC 20 000 mg/m³ (chronic, rat)
Effect on developmental toxicity
Dermal route:
No adverse effect observed NOAEL 500 mg/kg bw/day (subchronic, rat)
Inhalation route:
No adverse effect observed NOAEC 23 900 mg/m³ (subchronic, rat)

Neurotoxicity

Study results
  • 6 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study 2
Supporting study 4
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Immunotoxicity

Study results
  • 4 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study
Supporting study 4
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Endocrine disrupter mammalian screening - in vivo

Data not provided by the registrant