Registration Dossier
Registration Dossier
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EC number: 215-236-1 | CAS number: 1314-56-3
Endpoint summary
Administrative data
Description of key information
Key value for chemical safety assessment
Skin sensitisation
Endpoint conclusion
- Additional information:
- Migrated from Short description of key information:
According to EU regulation 1907/2006, Annex VII, column 2 a sensitisation study needs not to be conducted since Diphosphorus pentaoxide is classified as corrosive to the skin.
Respiratory sensitisation
Endpoint conclusion
- Additional information:
- Migrated from Short description of key information:
No data available
Justification for classification or non-classification
As above mentioned no sensitisation studies have to be conducted with Diphosphorus pentaoxide due to its corrosive properties.
Diphosphorus pentaoxide is a hygroscopic solid which forms with moisture/water an aqueous solution of phosphorus oxyacids (primary hydrolysis) that are subject to further (secondary) hydrolysis to the end product phosphoric acid, H3PO4. The exposure to Diphosphorus pentaoxide under physiological conditions (aqueous system) will principally lead to local effects due to the strong corrosivity of the generated phosphoric acid. Consequently, the effects caused by Phosphoric acid/Diphosphorus pentaoxide, respectively are solely based on secondary effects of corrosivity.
Allergic skin reactions or case reports of acute contact dermatitis to Diphosphorus pentaoxide have not been described in the literature and skin contact/contact with the respiratory system is very unlikly to occur due to the corrosivity of the substance.
Based on the exisiting data no statement on classification/non-classification with reference the sensitising properties can be made.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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