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EC number: 202-327-6 | CAS number: 94-36-0
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Toxicity to aquatic algae and cyanobacteria
Administrative data
Link to relevant study record(s)
Description of key information
Key value for chemical safety assessment
- EC50 for freshwater algae:
- 0.071 mg/L
- EC10 or NOEC for freshwater algae:
- 0.02 mg/L
Additional information
Two experimental results were available in order to assess the toxicity of Dibenzoyl peroxide to aquatic freshwater algae. However, these results were considered as unreliable or difficult to evaluate due to the insufficient documentation or unsuitable test systems. As a consequence, a new test was performed according to EEC method C.1 (1984) and OECD Test Guideline 201(1984) and GLP criteria. These three studies are summarised below:
- K3 Supporting Study (methodological deficiencies): in order to predict effects of chemicals in an aquatic environment, the toxicity to freshwater algae was assessed. The algal toxicity was determined in the Algal Growth Inhibition test in accordance with OECD, EEC and ISO test guidelines and with Monograph 26 (1996). The test was performed according to the OECD Principles of Good Laboratory Practice. The guidelines were slightly modified to ensure good growth and pH control of the cultures. Test item dissolved in OECD medium at approximately 10 mg/l forms a solution with particles. Therefore water accommodated fraction's (WAF's) were tested, prepared from stirring a solution of 9.6 mg/l for 24 hours and then filtrated. From this solution the following dilutions were prepared and tested: 1:32 - 1:16 - 1:8 - 1:4 and 1:2. Chemical analyses were performed as NPOC (non-purgeable organic carbon). Based on the NPOC concentration determined at the beginning of the test after filtration, the test concentrations were calculated as indicative values. Based on these indicative values the toxicity of these WAF's to exponentially growingPseudokirchneriella subcapitatawas determined over an exposure period of 72 hours. TheEbC50and ErC50(0-72 h) values based on the indicative concentrations of the test compound forP. subcapitataare 0.44 mg/l (0.31-0.62 mg/l 95% confidence limits) and 0.83 mg/l (0.59-1.13 mg/I 95% confidence limits), respectively. The indicative NOEC determined from the results is 0.12 mg/l, the LOEC is 0.23 mg/l.
- K4 Supporting Study (documentation insufficient for assessment): in another test the ECr50- 72h of Dibenzoyl peroxide was estimated at 0.44 mg/l (NIER, 2001).
- K1 Key Study: results are summarised in table below:
Algal growth inhibition assay
|
Initial measured Dibenzoyl peroxide (mg/L) |
Area under the growth curve |
|
EbC50(72 h) |
0.0422 [0.0230, 0.0661] |
No observed effect concentration (NOEC) |
0.02 |
Average specific growth rate |
|
ErC50 (0 - 72 h) |
0.0711 [0.0643, 0.0729] |
No observed effect concentration (NOEC) |
0.02 |
Yield |
|
EyC50 (0 - 72 h) |
0.0613 [0.0248, 0.0687] |
No observed effect concentration (NOEC) |
0.02 |
[95% confidence limits]
Therefore, Dibenzoyl peroxide can be considered as very toxic to aquatic freshwater algae.
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