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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Toxicological information

Developmental toxicity / teratogenicity

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Administrative data

Endpoint:
developmental toxicity
Type of information:
(Q)SAR
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
accepted calculation method
Justification for type of information:
The developmental toxicity potential has been estimated using Vega model v.1.2.2.
The complete estimation report has been attached into the IUCLID section 13..

Data source

Reference
Reference Type:
other: Estimation tool
Title:
N.A.
Author:
N.A.
Year:
2018
Bibliographic source:
N.A.

Materials and methods

Principles of method if other than guideline:
The developmental toxicity potential has been estimated using Vega model v.1.2.2.
GLP compliance:
not specified

Test material

Constituent 1
Reference substance name:
(+)-tartaric acid
IUPAC Name:
(+)-tartaric acid

Test animals

Species:
other: not applicable

Results and discussion

Results: maternal animals

Effect levels (maternal animals)

Remarks on result:
other: not expected as developmental toxicant, based on QSAR estimation

Maternal abnormalities

Abnormalities:
not specified

Results (fetuses)

Effect levels (fetuses)

Remarks on result:
other: not expected as developmental toxicant, based on QSAR estimation

Fetal abnormalities

Abnormalities:
not specified

Overall developmental toxicity

Developmental effects observed:
no

Applicant's summary and conclusion