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Environmental fate & pathways

Bioaccumulation: aquatic / sediment

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Description of key information

In accordance with Column 2 adaptation statement of REACH Regulation 1907/2006 Annex IX, information requirement section 9.3.2, a bioaccumulation study need not be conducted if the substance has low potential for bioaccumulation (e.g., log Kow < 3).  

Key value for chemical safety assessment

Additional information

The log Kow of trimellitic anhydride (TMA), determined experimentally according to the OECD 117 (HPLC method) is 0.06.

The log Kow of trimellitic acid (TMLA), determined experimentally according to OECD 107 (Shake Flask method) is 0.54.

The log Kow of trimellitic acid (TMLA), estimated at pH= 8 (environment, river) is -4.83.

The US EPA's KOWWIN model predicts a log Kow of 1.95 for TMA and a log Kow of 0.61 for its hydrolysis product TMLA. The log Kow value of ionised forms of TMLA relevant to considerations of environmental exposure is estimated to be negative. All these log10 Kow values lie below the trigger of 3.0 and both TMA and TMLA are therefore expected not to exhibit significant bioconcentration or bioaccumulation tendencies.

Studies of bioconcentration/bioaccumulation are not required for TMA (TMLA).