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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Physical & Chemical properties

Partition coefficient

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Administrative data

Link to relevant study record(s)

Description of key information

The following studies have been submitted to address the partition coefficient end point:
Walker JA & White DF (2010). Determination of water Solubility and Partition Coefficient (n-OCTANOL/WATER). Testing Laboratory: Harlan Laboratories Limited, Shardlow Business Park, Shardlow, Derbyshire, DE72 2GD, UK. Report Number: 3109/0041. Owner Company: Organo Tin REACH Consortium, c/o ReachCentrum, Avenue E. Van Nieuwenhuyse 6, B-1160, Brussels, BELGIUM
Tsuda et al. (1986) Bioconcentration of butyltin compounds by round crucian carp Toxicol. Environ. Chem. 12:137-143
Walker JA & White DF (2010) has been allocated a Klimisch score of 1 and is considered to be the key study. Tsuda et al. (1986) has been allocated a Klimisch Score of 2.
The partition coefficient of the test item has been determined to be 2.77 x 10ˆ4 at 20.8 ± 0.5°C, log10 Pow 4.44, using the shake-flask method, designed to be compatible with Method 107 of the OECD Guidelines for Testing of Chemicals, 27 July 1995.

Key value for chemical safety assessment

Log Kow (Log Pow):
at the temperature of:
20.8 °C

Additional information

A reliability rating of 1 was assigned to the key study (Walker & Wright, 2010), according to the criteria of Klimisch, 1997 as the study was conducted in accordance with recognised guidelines and GLP.

The following supporting information is also available for this endpoint:

- Tsuda et al. (1986) Bioconcentration of butyltin compounds by round crucian carp Toxicol. Environ. Chem. 12:137-143

This study has been conducted in line with OECD Guideline 107 but there is no information on the GLP status of the study and so it has been allocated a Klimisch score of 2.

Result: The octanol-water partition coefficients (Pow) of organotin compounds including dibutyltin dilaurate was measured three times by flask-shaking method and the log Pow was determined to be 3.12 for dibutyltin dilaurate.