Registration Dossier
Registration Dossier
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EC number: 234-685-4 | CAS number: 12023-91-5
Endpoint summary
Administrative data
Description of key information
Oral: LD50 > 2000 mg/kg b.w.
Dermal: LD50 > 2000 mg/kg b.w.
Inhalation: LD50 > 5 mg/L
No acute toxicity was observed up to the maximum achievable test concentration.
Key value for chemical safety assessment
Acute toxicity: via oral route
Endpoint conclusion
- Dose descriptor:
- discriminating dose
- Value:
- 2 000 mg/kg bw
Acute toxicity: via inhalation route
Endpoint conclusion
- Dose descriptor:
- discriminating conc.
- Value:
- 5 000 mg/m³ air
Acute toxicity: via dermal route
Endpoint conclusion
- Dose descriptor:
- discriminating dose
- Value:
- 2 000 mg/kg bw
Additional information
The inhalation route is considered to be the most appropriate route of administration.
Oral route:
The acute oral toxicity of strontium ferrite was assessed in a limit test according to OECD 423. 2000 mg/kg bw of the test item were administered orally to Wistar-rats. Observation period was 14 days. No mortalities or other adverse effects were observed. It can therefore be concluded that the oral LD50 is above the tested concentration of 2000 mg/kg b.w.
Dermal route:
The acute dermal toxicity of strontium ferrite was assessed in a limit test according to OECD 402 and UN-GHS. 2000 mg/kg bw of the test item was applied on the skin of Wistar-rats. The exposure period was 24 hours followed by an observation period of 14 days. No mortalities or other adverse effects were observed. It can therefore be concluded that the dermal LD50 is above the tested concentration of 2000 mg/kg b.w.
Inhalation route:
The acute inhalation toxicity of strontium ferrite was assessed in a limit test according to OECD 403 and UN-GHS. The technically achievable maximum concentration of 5 mg/L resulted in an actual average concentration of 0.61 mg/L which was appllied to Sprague Dawley rats. The exposure period was 4 hours followed by an observation period of 14 days. No mortalities or other adverse effects were observed.
Based on the above results strontium ferrite did not show acute inhalation toxicity at the maximum attainable concentration of 0.61 mg/L. Strontium ferrite showed to be non-toxic via the inhalative route in this test.
Justification for classification or non-classification
Strontium ferrite did not show any acute toxicity via the oral and dermal and inhalation route. Classification is not required.
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