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EC number: 270-727-8 | CAS number: 68477-38-3 A complex combination of hydrocarbons obtained by distilling cracked steam cracked distillate and/or its fractionation products. It consists of hydrocarbons having carbon number predominantly in the range of C10 to low molecular weight polymers.
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Acute Toxicity: oral
Administrative data
- Endpoint:
- acute toxicity: oral
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- other: GLP compliant, guideline study, available as unpublished report, no restrictions, fully adequate for assessment
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 1 989
- Report date:
- 1989
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 401 (Acute Oral Toxicity)
- GLP compliance:
- yes
- Test type:
- standard acute method
- Limit test:
- yes
Test material
- Reference substance name:
- Residues (petroleum), steam-cracked
- EC Number:
- 265-193-8
- EC Name:
- Residues (petroleum), steam-cracked
- Cas Number:
- 64742-90-1
- IUPAC Name:
- Residues (petroleum), steam-cracked
- Reference substance name:
- carbon black oil
- IUPAC Name:
- carbon black oil
- Details on test material:
- - Name of test material (as cited in study report): carbon black oil
- Substance type: Mixture of high boiling aromatic hydrocarbons
- Physical state: dark brown liquid
- Analytical purity: not applicable
- Density : 1.03 - 1.11 g/cm3 at 288.7 K
- Boiling point (initial, average) : 428 K at 1 x 10E5 Pa
- Composition of test material: alicyclic- and arylbenzenes, bi- and tricyclic aromatic compounds, asphalthenes and other high boiling hydrocarbons.
Carbon Black Oil contains less than 3 weight-% of polycyclic aromatic hydrocarbons (PCA)
- Storage condition of test material: room temperature
Constituent 1
Constituent 2
Test animals
- Species:
- rat
- Strain:
- other: Wistar outbred rats (Crl:Wl(WU)BR)
- Sex:
- male/female
- Details on test animals or test system and environmental conditions:
- TEST ANIMALS
- Source: Breeding Centre for Laboratory Animals "Charles River Wiga GmbH", Sulzfeld, F.R. Germany
- Age at study initiation: Approximately 6-7 weeks
- Weight at study initiation: 146 to 183 g for males, 123 to 141 g for females
- Fasting period before study: Yes (overnight)
- Housing: 5/cage, sexes separately, in stainless steel cages with wire-screen bottom and front
- Diet: TNO Institute's cereal-based, open-formula basal diet for rats ad libitum (except overnight prior to dosing)
- Water: Tap water ad libitum
- Acclimation period: Approximately 11 days
ENVIRONMENTAL CONDITIONS
- Temperature: 20-24°C
- Humidity: 30-70%
- Air changes (per hr): 10
- Photoperiod: 12 hrs dark / 12 hrs light
IN-LIFE DATES: From: 7 July 1989 To: 21 July 1989
Administration / exposure
- Route of administration:
- oral: gavage
- Vehicle:
- maize oil
- Details on oral exposure:
- VEHICLE
Concentration in vehicle: 20 g/100 mL maize oil
DOSE VOLUME APPLIED: 10 mL/kg bodyweight - Doses:
- 2000 mg/kg bodyweight
- No. of animals per sex per dose:
- 5
- Control animals:
- no
- Details on study design:
- - Duration of observation period following administration: 14 days
- Frequency of observations and weighing: The rats were observed frequently for signs of intoxication during the first 4 post-treatment hours and later on, at least once daily, throughout an observation period of 14 days. Individual body weights were recorded on day 0, 3, 7 and 14.
- Necropsy of survivors performed: yes
Results and discussion
Effect levels
- Sex:
- male/female
- Dose descriptor:
- LD50
- Effect level:
- > 2 000 mg/kg bw
- Remarks on result:
- other: no mortality at only dose tested. No adverse clinical signs after 48 hours, no treatment-related necropsy findings
- Mortality:
- No mortality
- Clinical signs:
- other: At 1 and 4 hours after treatment all male and female rats showed severe signs of sluggishness and moderate to severe signs of piloerection. At 24 hours after treatment all female rats showed moderate signs of piloerection and soiled fur. These signs of in
- Gross pathology:
- No treatment-related gross alterations
Applicant's summary and conclusion
- Interpretation of results:
- not classified
- Remarks:
- Migrated information Criteria used for interpretation of results: EU
- Conclusions:
- The acute oral LD50 for carbon black oil to male and female rats is greater than 2000 mg/kg bw
- Executive summary:
The acute oral toxicity of carbon black oil (CAS 64742-90-1) was determined in a group of 5 male and 5 female rats dosed at 2000 mg/kg bw using maize oil as the vehicle. Animals were observed for 14 days and necropsied at termination.
There were no mortalities or abnormalities at necropsy. Clinical signs of toxicity included sluggishness, piloerection and soiled fur which were completely reversed by 48 hours after dosing.
The LD50 is > 2000 mg/kg and carbon black oil (CAS 64742-90-1) does not warrant classification under GHS/CLP.
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