Registration Dossier
Registration Dossier
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EC number: 262-679-1 | CAS number: 61260-55-7
Toxicity to microorganisms
Administrative data
Link to relevant study record(s)
Description of key information
The substance is acutely harmful to aquatic microorganisms (LC50=38.85 mg/L). An EC10 of 21.75 mg/L after 16.7 hours was determined.
Key value for chemical safety assessment
- EC50 for microorganisms:
- 38.85 mg/L
- EC10 or NOEC for microorganisms:
- 21.75 mg/L
Additional information
The toxicity of the substance to Pseudomonas putida was tested using a growth inhibition test set up according to DIN38412, part 8, under GLP (93 -0200 -DGO). In the first test at test termination after 16.7 hours of exposure an EC50 of 40.4 mg/L and an EC10 of 24.4 mg/L were determined. In the repeated test an EC50 of 37.3 mg/L and an EC10 of 19.1 mg/L were determined. The resulting mean effect values for chemical safety assessment are 38.85 mg/L as EC50 and 21.75 mg/L as EC10.
In a supporting study conducted according to 87/302/EEC under GLP, a static system with activated sludge was used, with a resulting EC50(3h) of >100 mg/L (Ciba-Geigy Ltd. 1992b).
In a second supporting non-GLP study (89 -0342 -DKO) conducted according to the Bringmann-Kühn bacterial toxicity test, an EC10 of 13.1 mg/L was determined. This study was not sufficiently documented therefore it was used as a supporting study (Kl. 4).
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