Registration Dossier
Registration Dossier
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EC number: 910-757-7 | CAS number: -
Endpoint summary
Administrative data
Description of key information
Additional information
The components of DVB-55 and DVB-HP are only slightly soluble in water (44 mg/L), have moderate vapor pressure (ca. 50 Pa at 20°C), and have moderate log Kow (3.80). Therefore, both volatilization from water, and partitioning to soil/sediment, are important processes affecting their environmental distribution. The DVB-55 substance has shown little or no biodegradation in biodegradation screening tests. A biodegradation simulation study in water/sediment microcosms demonstrates rapid dissipation of DVB/EVB with DT50 from 3.8 to 31.4 days and the formation of more polar metabolites. Mineralization of [14C]1,3 EVB to14CO2 reached 19.8 and 67.7% of applied radioactivity within 49 days at 50 and 500 µg/L, respectively. In microcosms that did not contain sediment, mineralisation was minimal (3%).
Measured fish BCF values in Cyprinus carpio for a representative reaction mass substance (57.0% of DVB; 37% EVB) were < 453 L/kg wet wt. A mid-point BCF value of 320 L/Kg (wet wt.) is used for the chemical safety assessment.
The bioconcentration potential (bioconcentration factor, BCF) of the four major constituents in divinylbenzene (DVB-55) have been assessed using a quantitative structure-activity relationship (QSAR) model (BCF baseline model v.02.06) as described by Dimitrov et al (2005) and implemented in OASIS CATALOGIC v 5.11.12. Constituents of DVB-55 are not bioaccumulative with high confidence, as BCF values range from 219 and 302 L/kg.
The QSAR predictions are within the same range, as measured in Carp, which is chosen as a key value for the chemical safety assessment.
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