Registration Dossier

Administrative data

Description of key information

Not irritating to skin according to a guideline study (OECD TG 404) and not irritating to eyes according to a guideline study (OECD TG 405).

Key value for chemical safety assessment

Skin irritation / corrosion

Endpoint conclusion
Endpoint conclusion:
no adverse effect observed (not irritating)

Eye irritation

Endpoint conclusion
Endpoint conclusion:
no adverse effect observed (not irritating)

Additional information

Skin irritancy of the test substance was determined in a guideline study (OECD TG 404) in rabbits. The test substance was found to be not irritating. Skin corrosivity of the test substance was determined in vitro in a guideline study (EU B.40). The test substance was found to be not corrosive.

Eye irritancy of the test substance was determined in a guideline study (OECD TG 405) in rabbits. The test substance was found to be not irritating to eyes in this study, which is decisive for classification. Eye irritancy of the test substance was also determined in vitro according to a draft guideline (OECD, Draft proposal for a new guideline: "Bovine Corneal Opacity and Permeability (BCOP) Test Method for Identifying Ocular Corrosives and Severe Irritants). There, the test substance was found to be slightly irritating, which is not decisive for classification.


Effect level: empty Endpoint conclusion: Adverse effect observed

Justification for classification or non-classification

The classification criteria for skin or eye irritation according to Regulation (EC) No. 1272/2008 are not met.