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Physical & Chemical properties

Partition coefficient

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Description of key information

TEGME (measured) :-1.12
TEGBE (measured): 0.56
TEGEE (calculated): -0.96

Key value for chemical safety assessment

Log Kow (Log Pow):
at the temperature of:
20 °C

Additional information

There is no measured value available for the partition co-efficient of this substance. There is however measured data for two substances either side of it in the homologous series of these triethylene glycol ethers. 2-(2-(2 -methoxyyethoxy)ethoxy)ethanol (TEGME) has a measured value of -1.12 for log kow whereas 2-(2-(2 -butoxyyethoxy)ethoxy)ethanol has a value of 0.51. The value for 2-(2-(2-ethoxyyethoxy)ethoxy)ethanol (TEGEE) will fall somewhere in between. The predicted values for the logkow using the Epiwin QSAR are shown below:

 Substance  Measured logKow  QSAR value
 TEGME  -1.12  -1.46
 TEGEE    -0.96
 TEGBE  0.51  0.02

The QSAR seems to underpredict by a value of about 0.35 to 0.45. A corrected value of around -0.6 is predicted for the logkow and used as the key parameter. A justification for read across/interpolation is attached to chapter 13 of the lead registrant's dossier.