Registration Dossier
Registration Dossier
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EC number: 915-035-5 | CAS number: -
Endpoint summary
Administrative data
Description of key information
An acute oral toxicity test indicated an LD50 > 5000 mg/kg for chromium(III) oxide, corresponding to ca 3400 mg Cr/kg bw.
LC50 for acute inhalation toxicity is >5.41 mg/L (5410 mg/m3) air (analytical).
Key value for chemical safety assessment
Acute toxicity: via oral route
Endpoint conclusion
- Dose descriptor:
- LD50
- Value:
- 3 400 mg/kg bw
Acute toxicity: via inhalation route
Endpoint conclusion
- Dose descriptor:
- LC50
- Value:
- 5 410 mg/m³ air
Acute toxicity: via dermal route
Endpoint conclusion
- Value:
- mg/kg bw
Additional information
No data was available on acute toxicity of the reaction mass of heptachromium tricarbide and trichromium dicarbide. Due to the fact that the release of chromium from chromium carbide is very similar to the release from chromium(III) oxide, the LD50 >3400 mg Cr/kg and LC50 >5410 mg/m3 air, obtained with chromium(III) oxide, can be used as such for chromium carbide.
The reaction mass of heptachromium tricarbide and trichromium dicarbide is practically insoluble and is therefore not likely to pass through the skin or enter the systemic circulation after dermal exposure. Acute toxic effects via the skin are thus not expected and this route can be considered as not relevant.
Justification for classification or non-classification
Based on the available data on chromium(III) oxide, no classification is suggested for acute toxicity of the reaction mass of heptachromium tricarbide and trichromium dicarbide.
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