Registration Dossier

Administrative data

Endpoint:
repeated dose toxicity: oral
Remarks:
other: read-across
Type of information:
migrated information: read-across from supporting substance (structural analogue or surrogate)
Adequacy of study:
weight of evidence
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: read-across

Data source

Referenceopen allclose all

Reference Type:
study report
Title:
Unnamed
Year:
2012
Reference Type:
study report
Title:
Unnamed
Year:
1990
Reference Type:
study report
Title:
Unnamed
Year:
1970

Materials and methods

Test guideline
Qualifier:
no guideline followed
Guideline:
other: read-across
GLP compliance:
no

Test material

Constituent 1
Reference substance name:
ethyl thioacetate
IUPAC Name:
ethyl thioacetate
Constituent 2
Reference substance name:
methylthio 2- (acetyloxy) propionate
IUPAC Name:
methylthio 2- (acetyloxy) propionate
Constituent 3
Reference substance name:
methylthio 2- (propionyloxy) propionate
IUPAC Name:
methylthio 2- (propionyloxy) propionate

Test animals

Species:
rat

Results and discussion

Effect levels

Remarks on result:
not measured/tested
Remarks:
Effect level not specified (migrated information)

Target system / organ toxicity

Critical effects observed:
not specified

Any other information on results incl. tables

Maximum recxommended daily dose : 0.11 mmol (LAZAR)

Applicant's summary and conclusion

Conclusions:
Maximum recxommended daily dose : 0.11 mmol (LAZAR)
Executive summary:

No classification needed for repeated dose toxicity