Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
repeated dose toxicity: oral
Remarks:
other: read-across
Type of information:
migrated information: read-across from supporting substance (structural analogue or surrogate)
Adequacy of study:
weight of evidence
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: read-across

Data source

Referenceopen allclose all

Reference Type:
study report
Title:
Unnamed
Year:
2012
Reference Type:
study report
Title:
Unnamed
Year:
1990
Reference Type:
study report
Title:
Unnamed
Year:
1970

Materials and methods

Test guideline
Qualifier:
no guideline followed
Guideline:
other: read-across
GLP compliance:
no

Test material

Constituent 1
Reference substance name:
ethyl thioacetate
IUPAC Name:
ethyl thioacetate
Constituent 2
Reference substance name:
methylthio 2- (acetyloxy) propionate
IUPAC Name:
methylthio 2- (acetyloxy) propionate
Constituent 3
Reference substance name:
methylthio 2- (propionyloxy) propionate
IUPAC Name:
methylthio 2- (propionyloxy) propionate

Test animals

Species:
rat

Results and discussion

Effect levels

Remarks on result:
not measured/tested
Remarks:
Effect level not specified (migrated information)

Target system / organ toxicity

Critical effects observed:
not specified

Any other information on results incl. tables

Maximum recxommended daily dose : 0.11 mmol (LAZAR)

Applicant's summary and conclusion

Conclusions:
Maximum recxommended daily dose : 0.11 mmol (LAZAR)
Executive summary:

No classification needed for repeated dose toxicity